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3.5.4.43: hydroxydechloroatrazine ethylaminohydrolase

This is an abbreviated version!
For detailed information about hydroxydechloroatrazine ethylaminohydrolase, go to the full flat file.

Reaction

hydroxyatrazine
+
H2O
=
N-isopropylammelide
+
ethylamine

Synonyms

adenosine aminohydrolase 3, artB, AtzB, EC 3.5.99.3, FRAAL1473, FraEuI1c_5875, HAEA, hydroxyatrazine ethylaminohydrolase, Hydroxyatrazine hydrolase, hydroxyatrazine N-ethylaminohydrolase, More

ECTree

     3 Hydrolases
         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
             3.5.4 In cyclic amidines
                3.5.4.43 hydroxydechloroatrazine ethylaminohydrolase

Natural Substrates Products

Natural Substrates Products on EC 3.5.4.43 - hydroxydechloroatrazine ethylaminohydrolase

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
4-(ethylamino)-2-hydroxy-6-(isopropylamino)-1,3,5-triazine + H2O
?
show the reaction diagram
4-(ethylamino)-6-(propan-2-ylamino)-1,3,5-triazin-2-ol + H2O
6-(propan-2-ylamino)-1,3,5-triazine-2,4-diol + ethanamine
show the reaction diagram
-
-
-
-
ir
hydroxyatrazine + H2O
N-isopropyl ammelide + ethanamine
show the reaction diagram
additional information
?
-
-
the isolated strain is capable of degrading atrazine. Displacement of the three substituents on the s-triazine ring is mediated by three enzymatic steps encoded by the genes atzA, atzB, and atzC. AtzB catalyzes hydroxyatrazine deamidation, yielding N-isopropylammelide
-
-
?