3.5.4.39: GTP cyclohydrolase IV

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For detailed information about GTP cyclohydrolase IV, go to the full flat file.

Reaction

Synonyms

GTP cyclohydrolase MptA, MptA

ECTree

     3 Hydrolases

         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds

             3.5.4 In cyclic amidines

                3.5.4.39 GTP cyclohydrolase IV

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Results	in table
1164	AA Sequence
1	Cloned(Commentary)
4	Inhibitors
1	KM Value [mM]
2	Metals/Ions
3	Molecular Weight [Da]
1	Natural Substrates/ Products (Substrates)
1	Organism
1	Oxidation Stability
6	Pathway
2	pH Optimum
1	pH Range
7	Protein Variants
1	Purification (Commentary)
1	Reaction
1	Reference
6	Substrates and Products (Substrate)
2	Subunits
2	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
3	Temperature Stability [°C]

Systematic Name

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Systematic Name on EC 3.5.4.39 - GTP cyclohydrolase IV

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SYSTEMATIC NAME

IUBMB Comments

GTP 7,8-8,9-dihydrolase (cyclizing, formate-releasing, diphosphate-releasing)

Requires Fe2+. A zinc protein. The enzyme is involved in methanopterin biosynthesis in methanogenic archaea. cf. GTP cyclohydrolase I (EC 3.5.4.16), GTP cyclohydrolase II (EC 3.5.4.25) and GTP cyclohydrolase IIa (EC 3.5.4.29).