3.5.3.8: formimidoylglutamase

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For detailed information about formimidoylglutamase, go to the full flat file.

Reaction

Synonyms

FIGase, formimidoyl-L-glutamate formiminohydrolase, formiminoglutamase, Formiminoglutamate hydrolase, formylglutamate amidohydrolase, HutF, N-formimino-L-glutamate formiminohydrolase, N-formimino-L-glutamate iminohydrolase, N-formiminoglutamate hydrolase

ECTree

     3 Hydrolases

         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds

             3.5.3 In linear amidines

                3.5.3.8 formimidoylglutamase

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Results	in table
5649	AA Sequence
1	CAS Registry Number
3	Cloned(Commentary)
3	Cofactor
2	Crystallization (Commentary)
4	General Information
6	Inhibitors
5	kcat/KM [mM/s]
8	KM Value [mM]
13	Metals/Ions
2	Molecular Weight [Da]
14	Natural Substrates/ Products (Substrates)
15	Organism
5	Pathway
14	PDB ID
3	pH Optimum
4	Protein Variants
5	Purification (Commentary)
1	Reaction
1	Reaction Type
15	Reference
4	Specific Activity [micromol/min/mg]
1	Storage Stability
15	Substrates and Products (Substrate)
2	Subunits
15	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
3	Temperature Stability [°C]
5	Turnover Number [1/s]

Substrates Products

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Substrates Products on EC 3.5.3.8 - formimidoylglutamase

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SUBSTRATE

PRODUCT                       

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

Reversibility
r=reversible
ir=irreversible
?=not specified

N-formimidoyl-L-glutamate + H2O

L-glutamate + formamide

11 entries

additional information

?

-

2 entries

N-formimidoyl-L-glutamate + H2O

L-glutamate + formamide

Bacillus subtilis

-

-

5743, 246689

-

-

?

N-formimidoyl-L-glutamate + H2O

L-glutamate + formamide

Bacillus subtilis SH-11

-

-

5743

-

-

?

N-formimidoyl-L-glutamate + H2O

L-glutamate + formamide

Cupriavidus necator

-

together with N-formylglutamate hydrolase (EC 3.5.1.68) the substrates are degraded to glutamate, formate and ammonium

246691

-

-

?

N-formimidoyl-L-glutamate + H2O

L-glutamate + formamide

Homo sapiens

-

-

34321

-

-

?

N-formimidoyl-L-glutamate + H2O

L-glutamate + formamide

Klebsiella aerogenes

-

-

246686

-

-

?

N-formimidoyl-L-glutamate + H2O

L-glutamate + formamide

Pseudomonas aeruginosa

Q9HU77

-

752765

-

-

?

N-formimidoyl-L-glutamate + H2O

L-glutamate + formamide

Pseudomonas aeruginosa ATCC 15692

Q9HU77

-

752765

-

-

?

N-formimidoyl-L-glutamate + H2O

L-glutamate + formamide

Pseudomonas putida

-

-

5766, 209406

-

-

?

N-formimidoyl-L-glutamate + H2O

L-glutamate + formamide

Salmonella enterica subsp. enterica serovar Typhimurium

-

-

172091

-

-

?

N-formimidoyl-L-glutamate + H2O

L-glutamate + formamide

Trypanosoma cruzi

Q4DSA0

-

733344

-

-

?

N-formimidoyl-L-glutamate + H2O

L-glutamate + formamide

Vibrio alginolyticus

-

-

246690, 246692

-

-

?

additional information

?

-

Trypanosoma cruzi

Q4DSA0

no activity with L-arginine, agmatine, L-acetylarginine, alpha-guanidinoglutaric acid, L-homoarginine, L-2-amino-3-guanidinopropionic acid, 3-guanidinopropionic acid, and 4-guanidinobutyric acid

733344

-

-

?

additional information

?

-

Trypanosoma cruzi

-

no activity with L-arginine, agmatine, L-acetylarginine, alpha-guanidinoglutaric acid, L-homoarginine, L-2-amino-3-guanidinopropionic acid, 3-guanidinopropionic acid, and 4-guanidinobutyric acid

733344

-

-

?