3.5.3.8: formimidoylglutamase

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For detailed information about formimidoylglutamase, go to the full flat file.

Reaction

Synonyms

FIGase, formimidoyl-L-glutamate formiminohydrolase, formiminoglutamase, Formiminoglutamate hydrolase, formylglutamate amidohydrolase, HutF, N-formimino-L-glutamate formiminohydrolase, N-formimino-L-glutamate iminohydrolase, N-formiminoglutamate hydrolase

ECTree

     3 Hydrolases

         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds

             3.5.3 In linear amidines

                3.5.3.8 formimidoylglutamase

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Results	in table
5649	AA Sequence
1	CAS Registry Number
3	Cloned(Commentary)
3	Cofactor
2	Crystallization (Commentary)
4	General Information
6	Inhibitors
5	kcat/KM [mM/s]
8	KM Value [mM]
13	Metals/Ions
2	Molecular Weight [Da]
14	Natural Substrates/ Products (Substrates)
15	Organism
5	Pathway
14	PDB ID
3	pH Optimum
4	Protein Variants
5	Purification (Commentary)
1	Reaction
1	Reaction Type
15	Reference
4	Specific Activity [micromol/min/mg]
1	Storage Stability
15	Substrates and Products (Substrate)
2	Subunits
15	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
3	Temperature Stability [°C]
5	Turnover Number [1/s]

Crystallization

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Crystallization on EC 3.5.3.8 - formimidoylglutamase

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CRYSTALLIZATION (Commentary)

ORGANISM

UNIPROT

LITERATURE

hanging drop method at room temperature, the crystal structure of the enzyme is determined in the presence of the inhibitors N-formimino-L-aspartate and N-guanidino-L-glutaric acid at resolutions of 1.9 and 1.4 A, respectively

Pseudomonas aeruginosa

Q9HU77

752765

hanging drop vapor diffusion method, using 25% PEG (w/v) 3350, 0.1 M sodium acetate (pH 4.6)

Trypanosoma cruzi

Q4DSA0

733344