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3.5.2.18: enamidase

This is an abbreviated version!
For detailed information about enamidase, go to the full flat file.

Reaction

6-oxo-1,4,5,6-tetrahydronicotinate
+ 2 H2O =
2-formylglutarate
+
NH3

Synonyms

enamidase

ECTree

     3 Hydrolases
         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
             3.5.2 In cyclic amides
                3.5.2.18 enamidase

Substrates Products

Substrates Products on EC 3.5.2.18 - enamidase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
1,4,5,6-tetrahydro-6-oxonicotinate + H2O
2-(enamine)glutarate + NH3
show the reaction diagram
-
-
-
?
2-(enamine)glutarate + H2O
(S)-2-formylglutarate + NH3
show the reaction diagram
-
-
-
?
6-oxo-1,4,5,6-tetrahydronicotinate + H2O
2-formylglutarate + NH3
show the reaction diagram