3.5.1.79: Phthalyl amidase
This is an abbreviated version!
For detailed information about Phthalyl amidase, go to the full flat file.
Reaction
Synonyms
Amidase, phthalyl, o-Phthalyl amidase
ECTree
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Systematic Name
Systematic Name on EC 3.5.1.79 - Phthalyl amidase
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Phthalyl-amide amidohydrolase
In the entry, "phthalyl" is used to mean "2-carboxybenzoyl". The enzyme from Xanthobacter agilis hydrolyses phthalylated amino acids, peptides, beta-lactams, aromatic and aliphatic amines. The substituent on nitrogen may be an alkyl group, but may also be complex, giving an amino acid or peptide derivative. Substitutions on the phthalyl ring include 6-F, 6-NH2, 3-OH, and a nitrogen in the aromatic ring ortho to the carboxy group attached to the amine. No cofactors are required