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3.5.1.70: aculeacin-A deacylase

This is an abbreviated version!
For detailed information about aculeacin-A deacylase, go to the full flat file.

Word Map on EC 3.5.1.70

Reaction

aculeacin A
+
H2O
=
palmitic acid
+
deacyl-aculeacin A

Synonyms

AAC, aac1, aculeacin A acylase, AuAAC, cyclic lipopeptide acylase, deacylase, aculeacin A

ECTree

     3 Hydrolases
         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
             3.5.1 In linear amides
                3.5.1.70 aculeacin-A deacylase

Cloned

Cloned on EC 3.5.1.70 - aculeacin-A deacylase

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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
expression in Streptomyces lividans
-
expression in Streptomyces lividans JT46
-
gene aac1, DNA and amino acid sequence determination and analysis
overexpression and overproduction in Streptomyces lividans JT46, Streptomyces albus J1074, Streptomyces ambofaciens ATCC151540, Streptomyces parvulus 2283, Streptomyces avermitilis K139 and Streptomyces griseus ATCC23345, using multi-copy vector pIJ702
-
recombinant enzyme covalently immobilized onto several epoxy-activated supports in order to obtain a robust biocatalyst to be used in industrial bioreactors. The best biocatalyst is obtained by attaching the enzyme on Sepabeads EC-EP5
-