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3.4.24.78: gpr endopeptidase

This is an abbreviated version!
For detailed information about gpr endopeptidase, go to the full flat file.

Word Map on EC 3.4.24.78

Reaction

Endopeptidase action with P4 Glu or Asp, P1 preferably Glu > Asp, P1' hydrophobic and P2' Ala =

Synonyms

germinating-specific protease, GPS, germination proteinase, GPR, tepA, YmfB

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.24 Metalloendopeptidases
                3.4.24.78 gpr endopeptidase

Engineering

Engineering on EC 3.4.24.78 - gpr endopeptidase

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PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
D127A
-
no activity of P41 against small acid-soluble spore protein, no autoprocessing of P46
D127E
-
no activity of P41 against small acid-soluble spore protein, no autoprocessing of P46
D127N
-
no activity of P41 against small acid-soluble spore protein, no autoprocessing of P46
D127S
-
no activity of P41 against small acid-soluble spore protein, no autoprocessing of P46
D153N
-
activity of P41 against small acid-soluble spore protein, autoprocessing of P46
D193N
-
no activity of P41 against small acid-soluble spore protein, no autoprocessing of P46
D211N
-
activity of P41 against small acid-soluble spore protein, autoprocessing of P46
D246N
-
partial activity of P41 against small acid-soluble spore protein, no autoprocessing of P46
D253N
-
activity of P41 against small acid-soluble spore protein, autoprocessing of P46
D256N
-
activity of P41 against small acid-soluble spore protein, autoprocessing of P46
E201Q
-
activity of P41 against small acid-soluble spore protein, autoprocessing of P46
E26Q
-
activity of P41 against small acid-soluble spore protein, autoprocessing of P46
E89Q
-
activity of P41 against small acid-soluble spore protein, autoprocessing of P46
H125Q
-
activity of P41 against small acid-soluble spore protein, autoprocessing of P46
H142Q
-
activity of P41 against small acid-soluble spore protein, autoprocessing of P46
K21P
-
activity of P41 against small acid-soluble spore protein, autoprocessing of P46
K223A
-
activity of P41 against small acid-soluble spore protein, autoprocessing of P46
K223E
-
activity of P41 against small acid-soluble spore protein, autoprocessing of P46
K223H
-
activity of P41 against small acid-soluble spore protein, autoprocessing of P46
K223M
-
activity of P41 against small acid-soluble spore protein, autoprocessing of P46
Q208E
-
activity of P41 against small acid-soluble spore protein, autoprocessing of P46
R202Q
-
activity of P41 against small acid-soluble spore protein, autoprocessing of P46
R224Q
-
activity of P41 against small acid-soluble spore protein, autoprocessing of P46
S199A
-
activity of P41 against small acid-soluble spore protein, no autoprocessing of P46
S210A
-
activity of P41 against small acid-soluble spore protein, autoprocessing of P46
S212A
-
activity of P41 against small acid-soluble spore protein, autoprocessing of P46
S218A
-
activity of P41 against small acid-soluble spore protein, autoprocessing of P46
S249A
-
partial activity of P41 against small acid-soluble spore protein, no autoprocessing of P46
T125N
-
activity of P41 against small acid-soluble spore protein, autoprocessing of P46
T173V
-
activity of P41 against small acid-soluble spore protein, autoprocessing of P46
T215V
-
activity of P41 against small acid-soluble spore protein, autoprocessing of P46
T74D
-
activity of P41 against small acid-soluble spore protein, autoprocessing of P46
Y72F
-
activity of P41 against small acid-soluble spore protein, autoprocessing of P46
additional information