3.4.24.33: peptidyl-Asp metalloendopeptidase
This is an abbreviated version!
For detailed information about peptidyl-Asp metalloendopeptidase, go to the full flat file.
Reaction
Cleavage of Xaa-/-Asp, Xaa-/-Glu and Xaa-/-cysteic acid bonds
=
Synonyms
Asp-N, Asp-N endoproteinase, AspN, AspN endoproteinase, endoprotease Asp-N, Endoproteinase Asp-N, endoproteinase AspN, Peptidyl-Asp metalloproteinase, Proteinase, peptidyl-Asp metallo-, X-Asp metalloendopeptidase
ECTree
Inhibitors
Inhibitors on EC 3.4.24.33 - peptidyl-Asp metalloendopeptidase
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acetonitrile
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1% v/v, activation at 5-10% v/v
Alpha-macroglobulin
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inhibition at a molar ratio of inhibitor to protease of about 18 to 1
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additional information
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not inhibited by PMSF
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1,10-phenanthroline
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Zn2+ does not restore after prolonged incubation
1,10-phenanthroline
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cannot be reactivated by Zn2+