3.4.21.B54: Pyrococcus abyssi serine endopeptidase
This is an abbreviated version!
For detailed information about Pyrococcus abyssi serine endopeptidase, go to the full flat file.
Reaction
high affinity for aromatic (Phe and Tyr) and hydrophobic amino acids (mainly Leu) in P1 position, specificity for aromatic moieties in P1' position
=
ECTree
Inhibitors
Inhibitors on EC 3.4.21.B54 - Pyrococcus abyssi serine endopeptidase
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4-(2-aminoethyl)-benzenesulfonyl fluoride
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90% inhibition
Ca2+
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0.01-0.1 M: 50-60% decrease in activity
KCl
-
0.2-0.45 M: no effect. 0.1 M: 30-40% decrease in activity
Mg2+
-
0.01-0.1 M: 50-60% decrease in activity
NaCl
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0.2-0.45 M: no effect. 0.1 M: 30-40% decrease in activity
phenylmethylsulfonyl fluoride
-
80% ihibition
Soybean trypsin inhibitor
-
100% inhibition
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