3.4.21.B42: hippostasin

This is an abbreviated version!
For detailed information about hippostasin, go to the full flat file.

Reaction

proteolytic cleavage of polypeptides, preferential cleavage site: Arg- =

Synonyms

brain-type KLK11, GK-11, glandular kallikrein K11, hippostatin, hK11, human kallikrein 11, kallikrein 11, kallikrein-like protease, kallikrein-related peptidase 11, KLK11, prostate-type KLK11, S01.257, tissue kallikrein, tissue kallikrein 11, TLSP

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.21 Serine endopeptidases

                3.4.21.B42 hippostasin

Advanced search results

Do not include text mining results

Include results (more...)

Include results (more...)

Results	in table
2	AA Sequence
8	Application
2	CAS Registry Number
4	Cloned(Commentary)
323	Disease/ Diagnostics
4	Expression
4	Inhibitors
5	KM Value [mM]
2	Localization
3	Molecular Weight [Da]
1	Natural Substrates/ Products (Substrates)
25	Organism
2	pH Optimum
1	Posttranslational Modification
1	Purification (Commentary)
2	Reaction
8	Reaction Type
22	Reference
73	Source Tissue
20	Substrates and Products (Substrate)
3	Subunits
43	Synonyms
5	Turnover Number [1/s]

Expression

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

Expression on EC 3.4.21.B42 - hippostasin

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide Go to Expression Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

EXPRESSION

ORGANISM

UNIPROT

LITERATURE

both isoforms of KLK11 (prostate-type and brain-type) are significantly higher in cancer tissues compared with their normal counterparts

Homo sapiens

-

709810

kallikrein 11 expression is significantly decreased in gastric cancer compared with that in normal gastric mucosa

Homo sapiens

-

718041

kallikrein-related peptidase 11 expression is decreased in prostate cancer cells compared to normal/benign prostate cells

Homo sapiens

-

718165

regarding prostate-type KLK11, there is a significant association between lower expression and higher tumor stage

Homo sapiens

-

709810