3.4.21.85: limulus clotting factor B
This is an abbreviated version!
For detailed information about limulus clotting factor B, go to the full flat file.
Word Map on EC 3.4.21.85
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3.4.21.85
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c3b
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platelet-derived
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endothelial
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convertase
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hemolytic
-
properdin
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pdgf-b
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immunoglobulin
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ba
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histocompatibility
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venom
-
macular
-
cobra
-
igm
-
lectin
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lupus
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complement-mediated
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uremic
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glomerulonephritis
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erythematosus
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opsonization
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autoantibody
-
zymosan
-
clumping
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allotypes
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nephritic
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mannose-binding
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anaphylatoxins
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membranoproliferative
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p-tefb
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fluid-phase
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hemoglobinuria
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b-deficient
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cdk9
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adipsin
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mannan-binding
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glomerulopathy
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opsonin
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immunofixation
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microangiopathic
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anti-factor
-
factor-b
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complement-activating
-
maculopathy
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decay-accelerating
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rnaps
-
c1-inhibitor
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c4b-binding
-
eculizumab
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hypocomplementemia
- 3.4.21.85
- c3b
-
platelet-derived
- endothelial
-
convertase
-
hemolytic
- properdin
- pdgf-b
- immunoglobulin
- ba
-
histocompatibility
- venom
-
macular
- cobra
- igm
- lectin
-
lupus
-
complement-mediated
-
uremic
- glomerulonephritis
- erythematosus
-
opsonization
- autoantibody
- zymosan
-
clumping
- allotypes
-
nephritic
-
mannose-binding
- anaphylatoxins
-
membranoproliferative
- p-tefb
-
fluid-phase
- hemoglobinuria
-
b-deficient
- cdk9
- adipsin
-
mannan-binding
- glomerulopathy
-
opsonin
-
immunofixation
-
microangiopathic
-
anti-factor
-
factor-b
-
complement-activating
- maculopathy
-
decay-accelerating
-
rnaps
- c1-inhibitor
-
c4b-binding
- eculizumab
-
hypocomplementemia
Reaction
Selective cleavage of -Arg98-/-Ile- bond in limulus proclotting enzyme to form active clotting enzyme =
Synonyms
factor B
ECTree
3.4.21.85 limulus clotting factor BAdvanced search results
results (
results (Substrates Products
Substrates Products on EC 3.4.21.85 - limulus clotting factor B
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
N-tert-Butoxycarbonyl-Met-Thr-Arg 4-methylcoumarin 7-amide + H2O
?
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?
tert-butoxycarbonyl-Asp-Pro-Arg 4-methylcoumarin 7-amide + H2O
?
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-
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?
tert-butoxycarbonyl-Gln-Arg-Arg 4-methylcoumarin 7-amide + H2O
?
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-
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?
Tert-Butoxycarbonyl-Leu-Thr-Arg 4-methylcoumarin 7-amide + H2O
?
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-
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?
Tert-Butoxycarbonyl-Val-Pro-Arg-4-methylcoumaryl-7-amide + H2O
?
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?
additional information
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3 protease zymogens, factor C, factor B, and proclotting enzyme are required for the sequential activation of the limulus clotting system. Factor B is activated by factor C (sensitive to lipopolysaccharide) and the resulting factor B activates proclotting enzyme to the clotting enzyme
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