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3.4.21.85: limulus clotting factor B

This is an abbreviated version!
For detailed information about limulus clotting factor B, go to the full flat file.

Word Map on EC 3.4.21.85

Reaction

Selective cleavage of -Arg98-/-Ile- bond in limulus proclotting enzyme to form active clotting enzyme =

Synonyms

factor B

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.21 Serine endopeptidases
                3.4.21.85 limulus clotting factor B

Natural Substrates Products

Natural Substrates Products on EC 3.4.21.85 - limulus clotting factor B

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
additional information
?
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3 protease zymogens, factor C, factor B, and proclotting enzyme are required for the sequential activation of the limulus clotting system. Factor B is activated by factor C (sensitive to lipopolysaccharide) and the resulting factor B activates proclotting enzyme to the clotting enzyme
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