3.4.21.64: peptidase K

This is an abbreviated version!
For detailed information about peptidase K, go to the full flat file.

Reaction

Hydrolysis of keratin, and of other proteins with subtilisin-like specificity. Hydrolyses peptide amides =

Synonyms

EC 3.4.21.14, EC 3.4.21.4, EC 3.4.4.16, endopeptidase K, mesophilic proteinase K, PROK, Proteinase K, Proteinase, Tritirachium album serine, Tritirachium album proteinase K, Tritirachium alkaline proteinase

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.21 Serine endopeptidases

                3.4.21.64 peptidase K

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Results	in table
4	Activating Compound
9	AA Sequence
15	Application
1	CAS Registry Number
4	Cloned(Commentary)
21	Crystallization (Commentary)
16	Disease/ Diagnostics
11	General Information
6	General Stability
41	Inhibitors
28	KM Value [mM]
3	Localization
23	Metals/Ions
5	Molecular Weight [Da]
7	Natural Substrates/ Products (Substrates)
1	Organic Solvent Stability
70	Organism
233	PDB ID
13	pH Optimum
4	pH Range
3	pH Stability
1	pI Value
1	Posttranslational Modification
27	Protein Variants
6	Purification (Commentary)
1	Reaction
1	Reaction Type
70	Reference
28	Source Tissue
4	Specific Activity [micromol/min/mg]
1	Storage Stability
75	Substrates and Products (Substrate)
5	Subunits
48	Synonyms
11	Temperature Optimum [°C]
2	Temperature Range [°C]
12	Temperature Stability [°C]
6	Turnover Number [1/s]

Disease

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of the Enzyme Summary Page.

Disease on EC 3.4.21.64 - peptidase K

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DISEASE

TITLE OF PUBLICATION

LINK TO PUBMED

Adenocarcinoma

A glycopeptide from adenocarcinoma tissue of human lung.

3219227

Carcinoma, Ehrlich Tumor

Evidence for the presence of a trypsin inhibitor within rabbit and mouse tumour cells.

880306

Carcinoma, Ehrlich Tumor

Inhibition of trypsin and chymotrypsin by thiols. Biphasic kinetics of reactivation and inhibition induced by sodium periodate addition.

226148

Malnutrition

Comparative changes between pancreas and pancreatic juice digestive enzyme contents during nutritional rehabilitation following severe protein malnutrition in the rat.

7681321

Neoplasms

Evidence for the presence of a trypsin inhibitor within rabbit and mouse tumour cells.

880306

Neoplasms

Inhibition of trypsin and chymotrypsin by thiols. Biphasic kinetics of reactivation and inhibition induced by sodium periodate addition.

226148

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