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3.4.17.22: metallocarboxypeptidase D

This is an abbreviated version!
For detailed information about metallocarboxypeptidase D, go to the full flat file.

Word Map on EC 3.4.17.22

Reaction

releases C-terminal Arg and Lys from polypeptides =

Synonyms

Carboxypeptidase D, carboxypeptidase-D, CPD, CPD-N, DCPD, duck carboxypeptidase D, gp180, metallocarboxypeptidase-D, More, p170, silver, svr

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.17 Metallocarboxypeptidases
                3.4.17.22 metallocarboxypeptidase D

KM Value

KM Value on EC 3.4.17.22 - metallocarboxypeptidase D

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.063 - 0.132
Dansyl-Ala-Arg
0.056 - 0.065
Dansyl-Leu-Ala-Arg
0.25
Dansyl-Leu-Arg
-
-
0.012 - 0.844
dansyl-Phe-Ala-Arg
0.047 - 0.15
dansyl-Phe-Gly-Arg
0.085
dansyl-Phe-Ile-Arg
-
-
0.042 - 0.048
dansyl-Phe-Leu-Arg
0.016 - 0.1
dansyl-Phe-Phe-Arg
0.11
dansyl-Phe-Pro-Arg
-
-
0.0092 - 0.054
Dansyl-Pro-Ala-Arg
0.115
Tyr-Gly-Gly-Phe-Leu-Arg
-
wild-type enzyme, pH 6.4, 37°C
0.0305
Tyr-Gly-Gly-Phe-Leu-Lys
-
wild-type enzyme, pH 6.4, 37°C
additional information
additional information
-
Km-values of domain 1 and 2
-