3.3.2.7: hepoxilin-epoxide hydrolase
This is an abbreviated version!
For detailed information about hepoxilin-epoxide hydrolase, go to the full flat file.
Word Map on EC 3.3.2.7
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3.3.2.7
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trioxilin
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arachidonic
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leukotriene
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equatorial
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fructose-6-phosphate
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trihydroxy
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glucosamine
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glucosamine-6-phosphate
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nomenclature
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6-phosphate
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oscillations
- 3.3.2.7
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trioxilin
-
arachidonic
-
leukotriene
-
equatorial
- fructose-6-phosphate
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trihydroxy
- glucosamine
- glucosamine-6-phosphate
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nomenclature
-
6-phosphate
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oscillations
Reaction
Synonyms
HEH, hepoxilin epoxide hydrolase, HX epoxide hydrolase, hydrolase, hepoxilin epoxide
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General Information
General Information on EC 3.3.2.7 - hepoxilin-epoxide hydrolase
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physiological function
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hepoxilins (HXs) and trioxilins (TrXs) are involved in physiological processes such as inflammation, insulin secretion and pain perception in human. They are metabolites of polyunsaturated fatty acids (PUFAs), including arachidonic acid, eicosapentaenoic acid and docosahexaenoic acid, formed by 12-lipoxygenase (LOX) and epoxide hydrolase (EH) expressed by mammalian cells. Hepoxilin epoxide hydrolase converts hepoxilins into trioxilins through hydrolysis of the epoxy group