3.3.2.14: 2,4-dinitroanisole O-demethylase

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For detailed information about 2,4-dinitroanisole O-demethylase, go to the full flat file.

Reaction

Synonyms

2,4-dinitroanisole ether hydrolase, DNAN demethylase, DNAN O-demethylase, dnhA, dnhB

ECTree

     3 Hydrolases

         3.3 Acting on ether bonds

             3.3.2 Ether hydrolases

                3.3.2.14 2,4-dinitroanisole O-demethylase

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13	AA Sequence
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1	Cofactor
2	General Information
4	Molecular Weight [Da]
3	Natural Substrates/ Products (Substrates)
3	Organism
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4	pH Optimum
1	Protein Variants
3	Purification (Commentary)
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3	Reference
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1	Specific Activity [micromol/min/mg]
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2	Temperature Optimum [°C]

Systematic Name

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Systematic Name on EC 3.3.2.14 - 2,4-dinitroanisole O-demethylase

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SYSTEMATIC NAME

IUBMB Comments

2,4-dinitroanisole methanol hydrolase

The enzyme, characterized from the bacterium Nocardioides sp. JS1661, is involved in the degradation of 2,4-dinitroanisole. Unlike other known O-demethylases, such as EC 1.14.99.15, 4-methoxybenzoate monooxygenase (O-demethylating), or EC 1.14.11.32, codeine 3-O-demethylase, it does not require oxygen or electron donors, and produces methanol rather than formaldehyde.