3.2.1.B3: sucrose 6-phosphate hydrolase

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For detailed information about sucrose 6-phosphate hydrolase, go to the full flat file.

Word Map on EC 3.2.1.B3

3.2.1.B3

phosphotransferase

pt

phosphoenolpyruvate-dependent

fructokinase

fructose

disaccharide

pneumoniae

repressor

mutans

Reaction

beta-D-fructofuranosyl 6-O-phosphono-alpha-D-glucopyranoside

Synonyms

S-6-P hydrolase, scrB, scrB protein, ScrH, sucrose 6-phosphate hydrolase, sucrose-6-P hydrolase, sucrose-6-P-hydrolase, Sucrose-6-phosphate hydrolase, SusH

ECTree

3 Hydrolases

3.2 Glycosylases

3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds

3.2.1.B3 sucrose 6-phosphate hydrolase

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Results	in table
1	Activating Compound
3	AA Sequence
3	Cloned(Commentary)
2	General Information
4	Inhibitors
5	KM Value [mM]
1	Metals/Ions
2	Molecular Weight [Da]
5	Natural Substrates/ Products (Substrates)
8	Organism
1	pH Optimum
1	pH Range
2	Purification (Commentary)
1	Reaction
8	Reference
1	Specific Activity [micromol/min/mg]
13	Substrates and Products (Substrate)
5	Subunits
15	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]

Natural Substrates Products

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Natural Substrates Products on EC 3.2.1.B3 - sucrose 6-phosphate hydrolase

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beta-D-fructofuranosyl 6-O-phosphono-alpha-D-glucopyranoside + H2O

alpha-D-glucose 6-phosphate + beta-D-fructose

Streptococcus mutans

P13522

i.e. sucrose 6-phosphate, important enzyme in the transport and metabolism of dietary sucrose. Streptococcus mutans coordinates the activities of enzyme IIscr and sucrose-6-phosphate hydrolase by transcriptional repressor ScrR binding to the promoter regions of the scr regulon

651726

sucrose + H2O

alpha-D-glucose + beta-D-fructose

Streptococcus pneumoniae

sucrose uptake and catabolism play important roles in colonization of the murine nasopharynx and an accessory role in the infection of the lung, but is dispensable in a model of bacteraemia. The two sucrose uptake systems are differentially expressed such that one is dominant during lung infection while the other is dominant in colonization of the nasopharynx. Sucrose is a major carbon source utilized by Streptococcus pneumoniae during colonization and infection of mucosal surfaces

682006

sucrose 6-phosphate + H2O

alpha-D-glucose 6-phosphate + beta-D-fructose

Klebsiella pneumoniae

P27217

metabolism of sucrose, alpha-D-glucose 6-phosphate + beta-D-fructose are metabolized via the glycolytic pathway to yíeld primary lactic acid

646685

sucrose 6-phosphate + H2O

D-glucose 6-phosphate + D-fructose

2 entries