3.2.1.B23: ginsenosidase type II
This is an abbreviated version!
For detailed information about ginsenosidase type II, go to the full flat file.
Reaction
Sequential hydrolysis of the 20-O-beta-D-(1->6)-glucopyranosyl bond (leaving a single glucosyl residue at that position) followed by hydrolysis of the 3-O-beta-D-(1->2)-glucopyranosyl bond and the 3-O-beta-D-glucopyranosyl bond in protopanaxadiol-type ginsenosides =
Synonyms
alpha-L-arabinofuranosidase, alpha-L-arabinopyranosidase, beta-galactosidase, beta-glucosidase, beta-glucosidase GI, beta-glucosidase GII, ginsenosidase type II, ginsenosidase type II-i-1, ginsenosidase type II-i-2, ginsenosidase type II-i-4, ginsenosidase type II-ii
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General Information
General Information on EC 3.2.1.B23 - ginsenosidase type II
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evolution
physiological function
evolution
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the enzyme belongs to the glycosyl hydrolase family 1, GH1
evolution
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the enzyme belongs to the glycosyl hydrolase family 2, GH2
evolution
-
the enzyme belongs to the glycosyl hydrolase family 3, GH3
evolution
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the enzyme belongs to the glycosyl hydrolase family 3, GH3
evolution
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the enzyme belongs to the glycosyl hydrolase family 3, GH3
evolution
-
the enzyme belongs to the glycosyl hydrolase family 3, GH3
evolution
-
the enzyme belongs to the glycosyl hydrolase family 42, GH42
evolution
-
the enzyme belongs to the glycosyl hydrolase family 51, GH51
evolution
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the enzyme belongs to the glycosyl hydrolase family 51, GH51
evolution
-
the enzyme belongs to the glycosyl hydrolase family 51, GH51
evolution
-
the enzyme belongs to the glycosyl hydrolase family 51, GH51
-
evolution
Pseudothermotoga thermarum DSM 5069T
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the enzyme belongs to the glycosyl hydrolase family 1, GH1
-
-
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2
physiological function
-
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2
physiological function
-
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2
physiological function
-
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2
physiological function
-
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2
physiological function
-
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2
physiological function
-
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1 (Rb1->G17->G75). Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively, with the hydrolysis pattern of B (Rd->F2->C-K or Rg3->Rh2->APPD). Ginsenosidase type II-i-2 enzymes convert ginsenosides Rb2, C-O and C-Y to ginsenosides Rd, F2 and C-K as final products without further hydrolysis, respectively, through the hydrolysis of the outer arabinopyranose linked to C-20 with the hydrolysis pattern of A-2 (Rb2->C-O->C-Y)
physiological function
-
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1 (Rb1->G17->G75). Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively, with the hydrolysis pattern of B (Rd->F2->C-K or Rg3->Rh2->APPD). Ginsenosidase type II-i-2 enzymes convert ginsenosides Rb2, C-O and C-Y to ginsenosides Rd, F2 and C-K as final products without further hydrolysis, respectively, through the hydrolysis of the outer arabinopyranose linked to C-20 with the hydrolysis pattern of A-2 (Rb2->C-O->C-Y)
physiological function
-
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1 (Rb1->G17->G75). Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively, with the hydrolysis pattern of B (Rd->F2->C-K or Rg3->Rh2->APPD). Ginsenosidase type II-i-2 enzymes convert ginsenosides Rb2, C-O and C-Y to ginsenosides Rd, F2 and C-K as final products without further hydrolysis, respectively, through the hydrolysis of the outer arabinopyranose linked to C-20 with the hydrolysis pattern of A-2 (Rb2->C-O->C-Y)
physiological function
-
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1 (Rb1->G17->G75). Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively, with the hydrolysis pattern of B (Rd->F2->C-K or Rg3->Rh2->APPD). Ginsenosidase type II-i-2 enzymes convert ginsenosides Rb2, C-O and C-Y to ginsenosides Rd, F2 and C-K as final products without further hydrolysis, respectively, through the hydrolysis of the outer arabinopyranose linked to C-20 with the hydrolysis pattern of A-2 (Rb2->C-O->C-Y)
physiological function
-
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1 (Rb1->G17->G75). Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively, with the hydrolysis pattern of B (Rd->F2->C-K or Rg3->Rh2->APPD). Ginsenosidase type II-i-2 enzymes convert ginsenosides Rb2, C-O and C-Y to ginsenosides Rd, F2 and C-K as final products without further hydrolysis, respectively, through the hydrolysis of the outer arabinopyranose linked to C-20 with the hydrolysis pattern of A-2 (Rb2->C-O->C-Y)
physiological function
-
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1 (Rb1->G17->G75). Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively, with the hydrolysis pattern of B (Rd->F2->C-K or Rg3->Rh2->APPD). Ginsenosidase type II-ii enzymes also hydrolyze the outer sugar, including glucose, arabinopyranose or arabinofuranose linked to C-20 in the PPD-type ginsenosides with 4 different hydrolysis patterns
physiological function
-
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1 (Rb1->G17->G75). Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively, with the hydrolysis pattern of B (Rd->F2->C-K or Rg3->Rh2->APPD). Ginsenosidase type II-ii enzymes also hydrolyze the outer sugar, including glucose, arabinopyranose or arabinofuranose linked to C-20 in the PPD-type ginsenosides with 4 different hydrolysis patterns
physiological function
-
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1 (Rb1->G17->G75). Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively, with the hydrolysis pattern of B (Rd->F2->C-K or Rg3->Rh2->APPD). Ginsenosidase type II-ii enzymes also hydrolyze the outer sugar, including glucose, arabinopyranose or arabinofuranose linked to C-20 in the PPD-type ginsenosides with 4 different hydrolysis patterns
physiological function
-
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1 (Rb1->G17->G75). Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively, with the hydrolysis pattern of B (Rd->F2->C-K or Rg3->Rh2->APPD). Ginsenosidase type II-ii enzymes also hydrolyze the outer sugar, including glucose, arabinopyranose or arabinofuranose linked to C-20 in the PPD-type ginsenosides with 4 different hydrolysis patterns
physiological function
-
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1 (Rb1->G17->G75). Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively, with the hydrolysis pattern of B (Rd->F2->C-K or Rg3->Rh2->APPD). Ginsenosidase type II-ii enzymes also hydrolyze the outer sugar, including glucose, arabinopyranose or arabinofuranose linked to C-20 in the PPD-type ginsenosides with 4 different hydrolysis patterns
physiological function
-
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1 (Rb1->G17->G75). Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively, with the hydrolysis pattern of B (Rd->F2->C-K or Rg3->Rh2->APPD). Ginsenosidase type II-ii enzymes also hydrolyze the outer sugar, including glucose, arabinopyranose or arabinofuranose linked to C-20 in the PPD-type ginsenosides with 4 different hydrolysis patterns
physiological function
-
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1 (Rb1->G17->G75). Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively, with the hydrolysis pattern of B (Rd->F2->C-K or Rg3->Rh2->APPD). Ginsenosidase type II-ii enzymes also hydrolyze the outer sugar, including glucose, arabinopyranose or arabinofuranose linked to C-20 in the PPD-type ginsenosides with 4 different hydrolysis patterns
physiological function
-
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1 (Rb1->G17->G75). Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively, with the hydrolysis pattern of B (Rd->F2->C-K or Rg3->Rh2->APPD). Ginsenosidase type II-ii enzymes also hydrolyze the outer sugar, including glucose, arabinopyranose or arabinofuranose linked to C-20 in the PPD-type ginsenosides with 4 different hydrolysis patterns
physiological function
-
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-ii. Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively. Ginsenosidase type II-ii enzymes also hydrolyze the outer sugar, including glucose, arabinopyranose or arabinofuranose linked to C-20 in the PPD-type ginsenosides
physiological function
-
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-ii. Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively. Ginsenosidase type II-ii enzymes also hydrolyze the outer sugar, including glucose, arabinopyranose or arabinofuranose linked to C-20 in the PPD-type ginsenosides
physiological function
-
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-ii. Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively. Ginsenosidase type II-ii enzymes also hydrolyze the outer sugar, including glucose, arabinopyranose or arabinofuranose linked to C-20 in the PPD-type ginsenosides
physiological function
-
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-ii. Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively. Ginsenosidase type II-ii enzymes also hydrolyze the outer sugar, including glucose, arabinopyranose or arabinofuranose linked to C-20 in the PPD-type ginsenosides
physiological function
-
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-ii. Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively. Ginsenosidase type II-ii enzymes also hydrolyze the outer sugar, including glucose, arabinopyranose or arabinofuranose linked to C-20 in the PPD-type ginsenosides
physiological function
-
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2
-
physiological function
-
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1 (Rb1->G17->G75). Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively, with the hydrolysis pattern of B (Rd->F2->C-K or Rg3->Rh2->APPD). Ginsenosidase type II-i-2 enzymes convert ginsenosides Rb2, C-O and C-Y to ginsenosides Rd, F2 and C-K as final products without further hydrolysis, respectively, through the hydrolysis of the outer arabinopyranose linked to C-20 with the hydrolysis pattern of A-2 (Rb2->C-O->C-Y)
-
physiological function
-
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1 (Rb1->G17->G75). Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively, with the hydrolysis pattern of B (Rd->F2->C-K or Rg3->Rh2->APPD). Ginsenosidase type II-ii enzymes also hydrolyze the outer sugar, including glucose, arabinopyranose or arabinofuranose linked to C-20 in the PPD-type ginsenosides with 4 different hydrolysis patterns
-
physiological function
Aspergillus niger g.848
-
ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-ii. Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively. Ginsenosidase type II-ii enzymes also hydrolyze the outer sugar, including glucose, arabinopyranose or arabinofuranose linked to C-20 in the PPD-type ginsenosides
-
physiological function
Pseudothermotoga thermarum DSM 5069T
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ginsenosidase type II enzymes hydrolyze the sugars linked to C-20 in the PPD- and PPT-type ginsenosides, respectively. Type II enzymes are divided into types II-i-1, II-i-2, II-i-3, II-i-4 and II-2. Ginsenosidase type II-i-1 enzymes convert ginsenosides Rb1, G17 and G75 to ginsenosides Rd, F2 and CK as final products, respectively, by hydrolyzing only the outer glucose linked to C-20 but not the inner glucose linked to C-20 with the hydrolysis pattern of A-1 (Rb1->G17->G75). Ginsenosides Rd, F2, C-K, Re, Rg1, F1 and notoginsenoside R1 are converted to Rg3, Rh2, APPD, Rg2, Rh1, APPT and notoginsenoside R2 without further hydrolysis, respectively, by ginsenosidase type II-ii enzymes through the hydrolysis of the inner glucose at C-20 but not the sugar residues linked to C-3 and C-6 in the PPD- and PPT-type ginsenosides, respectively, with the hydrolysis pattern of B (Rd->F2->C-K or Rg3->Rh2->APPD). Ginsenosidase type II-ii enzymes also hydrolyze the outer sugar, including glucose, arabinopyranose or arabinofuranose linked to C-20 in the PPD-type ginsenosides with 4 different hydrolysis patterns
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