Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
2 nitric oxide + 2 ferrocytochrome c + 2 H+
nitrous oxide + 2 ferricytochrome c + H2O
2 nitric oxide + 2 reduced bovine heart cytochrome c + 2 H+
nitrous oxide + 2 oxidized bovine heart cytochrome c + H2O
-
-
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
N2O + acceptor + H2O
NO + reduced acceptor
-
-
-
-
r
N2O + phenazine methosulfate + H2O
NO + reduced phenazine methosulfate
nitric oxide + ferrocytochrome c552
nitrous oxide + ferricytochrome c552 + H2O
Marinobacter nauticus
-
-
-
-
?
nitric oxide + NAD(P)H + H+
nitrous oxide + NAD(P)+ + H2O
cytochrome P450nor is a nitric oxide reductase involved in fungal denitrification
-
-
?
nitric oxide + NADH
nitrous oxide + NAD+ + H2O
-
-
-
-
?
nitric oxide + NADH + H+
nitrous oxide + NAD+
cytochrome P450nor is a nitric oxide reductase involved in fungal denitrification
-
-
?
nitric oxide + NADH + H+
nitrous oxide + NAD+ + H2O
nitric oxide + oxidized acceptor + H+
nitrous oxide + reduced acceptor + H2O
-
-
-
-
?
nitric oxide + reduced acceptor
nitrous oxide + oxidized acceptor + H2O
nitric oxide + reduced ascorbate
nitrous oxide + oxidized ascorbate + H2O
Marinobacter nauticus
-
-
-
-
?
nitric oxide + reduced cytochrome c
nitrous oxide + cytochrome c + H2O
nitric oxide + reduced N,N,N',N'-tetramethyl-p-phenylenediamine
nitrous oxide + oxidized N,N,N',N'-tetramethyl-p-phenylenediamine + H2O
nitric oxide + reduced phenazine methosulfate
nitrous oxide + oxidized phenazine methosulfate + H2O
nitric oxide + reduced pseudoazurin
nitrous oxide + oxidized pseudoazurin + H2O
nitric oxide + reduced pseudoazurin
nitrous oxide + pseudoazurin + H2O
-
-
-
-
?
nitrous oxide + 2 ferricytochrome c + H2O
2 nitric oxide + 2 ferrocytochrome c + 2 H+
-
-
-
?
NO + 5-hydroxy-1,4-naphthoquinol
N2O + H2O + 5-hydroxy-1,4-naphthoquinone
-
-
-
-
?
NO + 5-hydroxy-2-methyl-1,4-naphthoquinol
N2O + H2O + 5-hydroxy-2-methyl-1,4-naphthoquinone
-
-
-
-
?
NO + menaquinol
N2O + H2O + menaquinone
-
-
-
-
?
NO + NADH
N2O + H2O + NAD+
NO + NADPH
N2O + H2O + NADP+
NO + reduced acceptor
N2O + H2O + acceptor
NO + reduced cytochrome c551
N2O + H2O + oxidized cytochrome c551
-
-
-
-
?
O2 + reduced acceptor + H+
H2O + oxidized acceptor
-
-
-
-
?
O2 + reduced cytochrome c
H2O + cytochrome c
-
-
-
-
?
additional information
?
-
2 nitric oxide + 2 ferrocytochrome c + 2 H+
nitrous oxide + 2 ferricytochrome c + H2O
-
-
-
-
?
2 nitric oxide + 2 ferrocytochrome c + 2 H+
nitrous oxide + 2 ferricytochrome c + H2O
-
-
-
?
2 nitric oxide + 2 ferrocytochrome c + 2 H+
nitrous oxide + 2 ferricytochrome c + H2O
-
-
-
-
?
2 nitric oxide + 2 ferrocytochrome c + 2 H+
nitrous oxide + 2 ferricytochrome c + H2O
-
-
-
?
2 nitric oxide + 2 ferrocytochrome c + 2 H+
nitrous oxide + 2 ferricytochrome c + H2O
-
-
-
?
2 nitric oxide + 2 ferrocytochrome c + 2 H+
nitrous oxide + 2 ferricytochrome c + H2O
D5GU62; D5GU63
-
-
-
?
2 nitric oxide + 2 ferrocytochrome c + 2 H+
nitrous oxide + 2 ferricytochrome c + H2O
D5GU62; D5GU63
-
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
-
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
as electron donors phenazine methosulfate, N,N,N',N'-tetramethyl-1,4-benzendiamine, N,N,N',N'-tetramethyl-1,4-benzendiamine together with horse cytochrome c
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
ascorbate plus 2,3,5,6-tetramethyl-1,4-benzendiamine as electron donors
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
-
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
-
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
cytochrome c as mediator
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
-
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
cytochrome c as mediator
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
-
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
-
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
cytochrome c as mediator
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
quinol-oxidising enzyme
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
-
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
quinol-oxidising enzyme
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
ascorbate and phenazine methosulfate, NADH, NADH/menadione, NADH/duroquinone, NADH/2,3-dimethoxy-5-methyl-1,4-benzoquinone and N,N,N',N'-tetramethyl-1,4-benzendiamine/ascorbate as electron donors
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
-
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
-
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
-
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
-
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
To degrade NO, FlRd has to be reduced by NADH via the FAD-binding protein flavorubredoxin reductase. NADH, but not NADPH, quickly reduces the FlRd-reductase. The reductase in turn quickly reduces the rubredoxin (Rd) center of FlRd
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
-
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
NAD(P)H and NAD(P)+ as electron donor/acceptor
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
-
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
NAD(P)H and NAD(P)+ as electron donor/acceptor
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
-
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
NAD(P)H and NAD(P)+ as electron donor/acceptor
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
quinol-oxidising enzyme
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
-
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
as electron donors phenazine methosulfate, N,N,N',N'-tetramethyl-1,4-benzendiamine, N,N,N',N'-tetramethyl-1,4-benzendiamine together with horse cytochrome c
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
ascorbate/phenazine methosulfate as electron donors
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
cytochrome c as mediator
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
quinol-oxidising enzyme
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
quinol-oxidising enzyme
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
quinol-oxidising enzyme
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
-
395112, 395114, 395115, 395116, 395118, 395120, 395124, 395127, 395131, 395133, 395134, 395135, 395136, 395137, 395139, 395140, 395141, 671883, 671948, 671964, 672352, 674003 -
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
phenazine methosulfate and dithiothreitol as electron donors
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
NADH, succinate or ascorbate plus 2,3,5,6-tetramethyl-1,4-benzendiamine as electron donors in membrane vesicles
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
as electron donors phenazine methosulfate, N,N,N',N'-tetramethyl-1,4-benzendiamine, N,N,N',N'-tetramethyl-1,4-benzendiamine together with horse cytochrome c
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
ferrocytochrome c-550 as electron donor
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
ascorbate/phenazine methosulfate, N,N,N',N'-tetramethyl-1,4-benzendiamine/ascorbate, 2,3,5,6-tetramethyl-1,4-benzendiamine/ascorbate and NADH as electron donors
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
ascorbate plus 2,3,5,6-tetramethyl-1,4-benzendiamine as electron donors
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
investigation of proton and electron pathways, electron-transfer pathways are similar to those in oxygen-reducing heme-copper oxidases
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
NADH, succinate or isoascorbate plus 2,3,5,6-tetramethyl-1,4-benzendiamine as electron donors
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
ascorbate, phenazine methosulfate and horse heart cytochrome c as the electron donor/mediator system
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
N,N,N',N'-tetramethyl-1,4-benzendiamine/ascorbate as electron donors
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
isoascorbate/2,3,5,6-tetramethyl-1,4-benzendiamine as electron donors and horse heart cytochrome c as mediator
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
cytochrome c as mediator
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
key step in the pathway of denitrification that uses N-oxyanions and N-oxides as respiratory electron acceptors
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
-
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
key step in the pathway of denitrification that uses N-oxyanions and N-oxides as respiratory electron acceptors
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
-
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
N,N,N',N'-tetramethyl-1,4-benzendiamine/ascorbate as electron donors
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
-
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
-
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
ascorbate, phenazine methosulfate and horse heart cytochrome c as the electron donor/mediator system
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
cytochrome c as mediator
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
-
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
mechanism
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
ascorbate plus 2,3,5,6-tetramethyl-1,4-benzendiamine as electron donors
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
cytochrome c as mediator
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
-
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
ascorbate plus 2,3,5,6-tetramethyl-1,4-benzendiamine as electron donors
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
-
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
lactate, leuco-forms of thionine, brilliant cresyl blue and methylene blue as electron donors
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
cytochrome c as mediator
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
-
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
as electron donors phenazine methosulfate, N,N,N',N'-tetramethyl-1,4-benzendiamine, N,N,N',N'-tetramethyl-1,4-benzendiamine together with horse cytochrome c
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
ascorbate plus 2,3,5,6-tetramethyl-1,4-benzendiamine as electron donors
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
ascorbate/phenazine methosulfate as electron donors
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
cytochrome c as mediator
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
-
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
quinol-oxidising enzyme
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
-
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
reduced menadione as electron donor
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
quinol-oxidising enzyme
-
-
?
2 nitric oxide + reduced acceptor
nitrous oxide + acceptor + H2O
-
-
-
-
?
N2O + phenazine methosulfate + H2O
NO + reduced phenazine methosulfate
-
using NO donor sodium nitroprusside and a N2 atmosphere in presence of NADH
-
-
r
N2O + phenazine methosulfate + H2O
NO + reduced phenazine methosulfate
-
-
-
-
?
nitric oxide + NADH + H+
nitrous oxide + NAD+ + H2O
cytochrome P450nor is a nitric oxide reductase involved in fungal denitrification
-
-
?
nitric oxide + NADH + H+
nitrous oxide + NAD+ + H2O
-
-
-
-
r
nitric oxide + NADH + H+
nitrous oxide + NAD+ + H2O
cytochrome P450nor is a nitric oxide reductase involved in fungal denitrification
-
-
?
nitric oxide + reduced acceptor
nitrous oxide + oxidized acceptor + H2O
Marinobacter nauticus
-
-
-
-
?
nitric oxide + reduced acceptor
nitrous oxide + oxidized acceptor + H2O
-
-
-
-
?
nitric oxide + reduced acceptor
nitrous oxide + oxidized acceptor + H2O
-
-
-
-
?
nitric oxide + reduced cytochrome c
nitrous oxide + cytochrome c + H2O
-
-
-
-
?
nitric oxide + reduced cytochrome c
nitrous oxide + cytochrome c + H2O
-
-
-
-
?
nitric oxide + reduced N,N,N',N'-tetramethyl-p-phenylenediamine
nitrous oxide + oxidized N,N,N',N'-tetramethyl-p-phenylenediamine + H2O
-
-
-
-
?
nitric oxide + reduced N,N,N',N'-tetramethyl-p-phenylenediamine
nitrous oxide + oxidized N,N,N',N'-tetramethyl-p-phenylenediamine + H2O
-
-
-
-
?
nitric oxide + reduced phenazine methosulfate
nitrous oxide + oxidized phenazine methosulfate + H2O
-
-
-
-
?
nitric oxide + reduced phenazine methosulfate
nitrous oxide + oxidized phenazine methosulfate + H2O
-
-
-
-
?
nitric oxide + reduced pseudoazurin
nitrous oxide + oxidized pseudoazurin + H2O
-
-
-
-
?
nitric oxide + reduced pseudoazurin
nitrous oxide + oxidized pseudoazurin + H2O
-
-
-
-
?
NO + NADH
N2O + H2O + NAD+
-
-
-
?
NO + NADH
N2O + H2O + NAD+
NADH is preferred over NADPH
-
-
?
NO + NADH
N2O + H2O + NAD+
-
-
-
-
?
NO + NADH
N2O + H2O + NAD+
-
NADH is preferred over NADPH
-
-
?
NO + NADH
N2O + H2O + NAD+
-
-
-
-
?
NO + NADH
N2O + H2O + NAD+
-
very little activity with NADPH
-
-
?
NO + NADH
N2O + H2O + NAD+
-
-
-
-
?
NO + NADH
N2O + H2O + NAD+
-
very little activity with NADPH
-
-
?
NO + NADPH
N2O + H2O + NADP+
-
-
-
?
NO + NADPH
N2O + H2O + NADP+
-
-
-
-
?
NO + reduced acceptor
N2O + H2O + acceptor
-
-
-
-
?
NO + reduced acceptor
N2O + H2O + acceptor
-
FlRd may protect Escherichia coli against NO, catalyzing the anaerobic reduction of NO to N2O
-
-
?
NO + reduced acceptor
N2O + H2O + acceptor
-
-
-
-
?
NO + reduced acceptor
N2O + H2O + acceptor
-
-
-
-
?
NO + reduced acceptor
N2O + H2O + acceptor
-
-
-
-
?
NO + reduced acceptor
N2O + H2O + acceptor
-
-
-
-
?
additional information
?
-
-
both toxin Dtx and nitric oxide reductase are the two key players required for survival and pathogenesis of Corynebacterium diphtheriae, their expressions being controlled by two independent regulators DtxR and DIP1512 respectively. The controlling system appears to be decoupled because of differential affinities of the two regulators for NO
-
-
?
additional information
?
-
NO reduction takes place in the NorB subunit that contains three redox centers: two b-type hemes (hemes b and b3) and a non-heme iron (FeB). Heme b3 and the non-heme iron form the binuclear center, where nitric oxide is bound and reduced. Determination of reduction rates of the cNOR variants with O2 and NO
-
-
?
additional information
?
-
-
NO reduction takes place in the NorB subunit that contains three redox centers: two b-type hemes (hemes b and b3) and a non-heme iron (FeB). Heme b3 and the non-heme iron form the binuclear center, where nitric oxide is bound and reduced. Determination of reduction rates of the cNOR variants with O2 and NO
-
-
?
additional information
?
-
-
Pseudomonas aeruginosa NO reductase may contribute to the intracellular survival by acting as a counter component against the hosts defense systems
-
-
?
additional information
?
-
-
the dissimilative nitrate respiration regulator DNR is involved in transcription regulation of the enzyme, apo-DNR binds heme in vitro and the heme-bound form reacts with carbon monoxide and NO, thus supporting the hypothesis that NO sensing involves gas binding to the ferrous heme, mechanism and structure, overview
-
-
?
additional information
?
-
all-atom molecular dynamics simulations within an explicit membrane/solvent environment reveal two possible proton transfer pathways leading from the periplasm to the active site, while no pathways from the cytoplasmic side are found, consistently with the experimental observations that the enzyme is not a proton pump. One of the pathways is blocked in the crystal structure and requires small structural rearrangements to allow for water channel formation. That pathway is equivalent to the functional periplasmic cavity postulated in cbb3 oxidase
-
-
?
additional information
?
-
-
quantumchemical calculations show that the reduction of the NO molecules by the enzyme and the formation of N2O are very exergonic steps, making the rereduction of the enzyme endergonic and rate-limiting for the entire catalytic cycle. Therefore the NO reduction cannot be electrogenic, i.e. cannot take electrons and protons from the opposite sides of the membrane, since it would increase the endergonicity of the rereduction when the gradient is present, thereby increasing the rate-limiting barrier, and the reaction would become too slow. It also means that proton pumping coupled to electron transfer is not possible in cytochrome c-dependent nitric oxide reductase
-
-
?
additional information
?
-
all-atom molecular dynamics simulations within an explicit membrane/solvent environment reveal two possible proton transfer pathways leading from the periplasm to the active site, while no pathways from the cytoplasmic side are found, consistently with the experimental observations that the enzyme is not a proton pump. One of the pathways is blocked in the crystal structure and requires small structural rearrangements to allow for water channel formation. That pathway is equivalent to the functional periplasmic cavity postulated in cbb3 oxidase
-
-
?