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10.94
1,4-androstadien-17beta-ol-3-one
-
pH 6.0, 37°C
0.52 - 9.607
2-cyclohexen-1-one
0.93 - 2.77
4-androstene-3,17-dione
41.25
4-cholesten-7alpha-ol-3-one
-
pH 6.0, 37°C
15
4-estren-17beta-ol-3-one
-
pH 6.0, 37°C
60
aldosterone
-
pH 6.0, 37°C
2.609 - 43.08
androstenedione
33.33
cholestenone
-
pH 6.0, 37°C
14.54
corticosterone
-
pH 6.0, 37°C
34.48
Epitestosterone
-
pH 6.0, 37°C
0.052 - 0.628
progesterone
0.52
2-cyclohexen-1-one
wild-type, cofactor NADPH, pH 6, 40°C
0.588
2-cyclohexen-1-one
-
pH 8.0, 40°C, recombinant mutant Y156V
0.611
2-cyclohexen-1-one
mutant R63K/R64H, cofactor NADPH, pH 6, 40°C
1.19
2-cyclohexen-1-one
-
pH 8.0, 40°C, recombinant mutant Y156V/N205M
1.464
2-cyclohexen-1-one
-
pH 8.0, 40°C, recombinant wild-type enzyme
1.5
2-cyclohexen-1-one
mutant R63K/R64H, cofactor NADH, pH 6, 40°C
2.425
2-cyclohexen-1-one
-
pH 8.0, 40°C, recombinant mutant N205M
6.266
2-cyclohexen-1-one
-
pH 8.0, 40°C, recombinant mutant N205A
9.607
2-cyclohexen-1-one
pH 8.0, 40°C, recombinant wild-type enzyme
0.93
4-androstene-3,17-dione
isoform AKR1D4L, pH 7, 37°C
1
4-androstene-3,17-dione
isoform AKR1D4S, pH 7, 37°C
2.77
4-androstene-3,17-dione
-
pH 6.0, 37°C
2.609
androstenedione
pH 7.4, 37°C, mutant V309F
35.13
androstenedione
pH 7.4, 37°C, wild-type enzyme
43.08
androstenedione
pH 7.4, 37°C, mutant Y132F
3.44
cortisol
-
pH 6.0, 37°C
10.5
cortisol
isoform AKR1D4S, pH 7, 37°C
13
cortisol
isoform AKR1D4L, pH 7, 37°C
7.69
cortisone
pH 6.0, 37°C, mutant P133R
7.7
cortisone
mutant P133R, pH not specified in the publication, temperature not specified in the publication
10.93
cortisone
pH 6.0, 37°C, wild-type enzyme
11
cortisone
wild-type, pH not specified in the publication, temperature not specified in the publication
12.91
cortisone
-
pH 6.0, 37°C
0.052
progesterone
-
pH 8.0, 40°C, recombinant wild-type enzyme
0.105
progesterone
-
pH 8.0, 40°C, recombinant mutant Y156V
0.122
progesterone
-
pH 8.0, 40°C, recombinant mutant Y156V/N205M
0.313
progesterone
-
wild-type, pH 7.4, 37°C
0.35
progesterone
-
mutant Y132G, pH 7.4, 37°C
0.432
progesterone
-
pH 8.0, 40°C, recombinant mutant N205A
0.473
progesterone
-
pH 8.0, 40°C, recombinant mutant N205M
0.628
progesterone
pH 8.0, 40°C, recombinant wild-type enzyme
3.5
testosterone
mutant P133R, pH not specified in the publication, temperature not specified in the publication
3.54
testosterone
pH 6.0, 37°C, mutant P133R
4.44
testosterone
pH 6.0, 37°C, wild-type enzyme
43.8
testosterone
wild-type, pH not specified in the publication, temperature not specified in the publication
51.85
testosterone
-
pH 6.0, 37°C