1.14.99.48: heme oxygenase (staphylobilin-producing)
This is an abbreviated version!
For detailed information about heme oxygenase (staphylobilin-producing), go to the full flat file.
Word Map on EC 1.14.99.48
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1.14.99.48
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glutathione-s-transferase
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trophic
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eastern
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wastewaters
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mussels
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gonad
- 1.14.99.48
- glutathione-s-transferase
-
trophic
-
eastern
-
wastewaters
-
mussels
-
gonad
Reaction
+ 5 reduced acceptor + 4 O2 = + + + 5 acceptor + 4 H2O
Synonyms
haem oxidase, haem oxygenase, heme oxidase, heme oxygenase, heme oxygenase (decyclizing), heme oxygenase (staphylobilin-producing) 1, heme oxygenase (staphylobilin-producing) 2, isdG, isdI
ECTree
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Natural Substrates Products
Natural Substrates Products on EC 1.14.99.48 - heme oxygenase (staphylobilin-producing)
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REACTION DIAGRAM
15-oxo-beta-bilirubin + Fe2+ + CO + 4 A + 4 H2O
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enzyme cleaves the tetrapyrrol ring structure of heme in the presence of NADPH cytochrome P450 reductase, thereby releasing iron
-
?
protoheme + 4 AH2 + 4 O2
15-oxo-beta-bilirubin + Fe2+ + CO + 4 A + 4 H2O
-
oxidoreductase IruO, gene name NWMN2274, is the likely in vivo reductant required for heme degradation by Staphylococcus aureus. In the presence of NADPH and IruO, either IsdI or IsdG degrade bound heme 10fold more rapidly than with the chemical reductant ascorbic acid. The major heme degradation products are 5-oxo-delta-bilirubin and 15-oxo-beta-bilirubin, i.e. staphylobilins
-
?
protoheme + 4 AH2 + 4 O2
15-oxo-beta-bilirubin + Fe2+ + CO + 4 A + 4 H2O
-
oxidoreductase IruO, gene name thatNWMN2274, is the likely in vivo reductant required for heme degradation by Staphylococcus aureus. In the presence of NADPH and IruO, either IsdI or IsdG degrade bound heme 10fold more rapidly than with the chemical reductant ascorbic acid. The major heme degradation products are 5-oxo-delta-bilirubin and 15-oxo-beta-bilirubin, i.e. staphylobilins
-
?
protoheme + 4 AH2 + 4 O2
15-oxo-beta-bilirubin + Fe2+ + CO + 4 A + 4 H2O
-
product is a red-orange solid that becomes yellow when dissolved in dimethyl sulfoxide or water/acetonitrile. It is more polar than biliverdin and bilirubin
-
?
protoheme + 4 AH2 + 4 O2
15-oxo-beta-bilirubin + Fe2+ + CO + 4 A + 4 H2O
-
product is a red-orange solid that becomes yellow when dissolved in dimethyl sulfoxide or water/acetonitrile. It is more polar than biliverdin and bilirubin
-
?
protoheme + 4 AH2 + 4 O2
15-oxo-beta-bilirubin + Fe2+ + CO + 4 A + 4 H2O
-
enzyme cleaves the tetrapyrrol ring structure of heme in the presence of NADPH cytochrome P450 reductase, thereby releasing iron
-
?
protoheme + 4 AH2 + 4 O2
15-oxo-beta-bilirubin + Fe2+ + CO + 4 A + 4 H2O
-
oxidoreductase IruO, gene name thatNWMN2274, is the likely in vivo reductant required for heme degradation by Staphylococcus aureus. In the presence of NADPH and IruO, either IsdI or IsdG degrade bound heme 10fold more rapidly than with the chemical reductant ascorbic acid. The major heme degradation products are 5-oxo-delta-bilirubin and 15-oxo-beta-bilirubin, i.e. staphylobilins
-
?
protoheme + 4 AH2 + 4 O2
15-oxo-beta-bilirubin + Fe2+ + CO + 4 A + 4 H2O
-
oxidoreductase IruO, gene name NWMN2274, is the likely in vivo reductant required for heme degradation by Staphylococcus aureus. In the presence of NADPH and IruO, either IsdI or IsdG degrade bound heme 10fold more rapidly than with the chemical reductant ascorbic acid. The major heme degradation products are 5-oxo-delta-bilirubin and 15-oxo-beta-bilirubin, i.e. staphylobilins
-
?
5-oxo-delta-bilirubin + Fe2+ + CO + 4 A + 4 H2O
-
enzyme cleaves the tetrapyrrol ring structure of heme in the presence of NADPH cytochrome P450 reductase, thereby releasing iron
-
?
protoheme + 4 AH2 + 4 O2
5-oxo-delta-bilirubin + Fe2+ + CO + 4 A + 4 H2O
-
oxidoreductase IruO, gene name NWMN2274, is the likely in vivo reductant required for heme degradation by Staphylococcus aureus. In the presence of NADPH and IruO, either IsdI or IsdG degrade bound heme 10fold more rapidly than with the chemical reductant ascorbic acid. The major heme degradation products are 5-oxo-delta-bilirubin and 15-oxo-beta-bilirubin, i.e. staphylobilins
-
?
protoheme + 4 AH2 + 4 O2
5-oxo-delta-bilirubin + Fe2+ + CO + 4 A + 4 H2O
-
oxidoreductase IruO, gene name thatNWMN2274, is the likely in vivo reductant required for heme degradation by Staphylococcus aureus. In the presence of NADPH and IruO, either IsdI or IsdG degrade bound heme 10fold more rapidly than with the chemical reductant ascorbic acid. The major heme degradation products are 5-oxo-delta-bilirubin and 15-oxo-beta-bilirubin, i.e. staphylobilins
-
?
protoheme + 4 AH2 + 4 O2
5-oxo-delta-bilirubin + Fe2+ + CO + 4 A + 4 H2O
-
product is a red-orange solid that becomes yellow when dissolved in dimethyl sulfoxide or water/acetonitrile. It is more polar than biliverdin and bilirubin
-
?
protoheme + 4 AH2 + 4 O2
5-oxo-delta-bilirubin + Fe2+ + CO + 4 A + 4 H2O
-
product is a red-orange solid that becomes yellow when dissolved in dimethyl sulfoxide or water/acetonitrile. It is more polar than biliverdin and bilirubin
-
?
protoheme + 4 AH2 + 4 O2
5-oxo-delta-bilirubin + Fe2+ + CO + 4 A + 4 H2O
-
enzyme cleaves the tetrapyrrol ring structure of heme in the presence of NADPH cytochrome P450 reductase, thereby releasing iron
-
?
protoheme + 4 AH2 + 4 O2
5-oxo-delta-bilirubin + Fe2+ + CO + 4 A + 4 H2O
-
oxidoreductase IruO, gene name thatNWMN2274, is the likely in vivo reductant required for heme degradation by Staphylococcus aureus. In the presence of NADPH and IruO, either IsdI or IsdG degrade bound heme 10fold more rapidly than with the chemical reductant ascorbic acid. The major heme degradation products are 5-oxo-delta-bilirubin and 15-oxo-beta-bilirubin, i.e. staphylobilins
-
?
protoheme + 4 AH2 + 4 O2
5-oxo-delta-bilirubin + Fe2+ + CO + 4 A + 4 H2O
-
oxidoreductase IruO, gene name NWMN2274, is the likely in vivo reductant required for heme degradation by Staphylococcus aureus. In the presence of NADPH and IruO, either IsdI or IsdG degrade bound heme 10fold more rapidly than with the chemical reductant ascorbic acid. The major heme degradation products are 5-oxo-delta-bilirubin and 15-oxo-beta-bilirubin, i.e. staphylobilins
-
?