1.13.11.4: gentisate 1,2-dioxygenase

This is an abbreviated version!
For detailed information about gentisate 1,2-dioxygenase, go to the full flat file.

Reaction

Synonyms

2,5-dihydroxybenzoate dioxygenase, DsmD, EC 1.13.1.4, EC 1.99.2.4, eGDO, GDO, GDO-II, gdoA, GDOsp, GenH, gentisate dioxygenase, gentisate oxygenase, gentisate-1,2-dioxygenase, gentisic acid oxidase, gtdA-2, hbzE, Nagl1, Nagl2, Nagl3, NarI, oxygenase, gentisate 1,2-di-, P25X gentisate 1,2-dioxygenase, P35X gentisate 1,2-dioxygenase, salicylate 1,2-dioxygenase, SDO

ECTree

     1 Oxidoreductases

         1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)

             1.13.11 With incorporation of two atoms of oxygen

                1.13.11.4 gentisate 1,2-dioxygenase

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Results	in table
16	Activating Compound
1405	AA Sequence
2	Application
1	CAS Registry Number
24	Cloned(Commentary)
5	Crystallization (Commentary)
4	Expression
15	General Information
14	General Stability
79	Inhibitors
19	kcat/KM [mM/s]
10	Ki Value [mM]
117	KM Value [mM]
30	Metals/Ions
44	Molecular Weight [Da]
26	Natural Substrates/ Products (Substrates)
124	Organism
4	Oxidation Stability
9	Pathway
17	PDB ID
22	pH Optimum
2	pH Range
11	pH Stability
8	pI Value
90	Protein Variants
31	Purification (Commentary)
3	Reaction
3	Reaction Type
76	Reference
2	Renatured (Commentary)
8	Source Tissue
25	Specific Activity [micromol/min/mg]
21	Storage Stability
246	Substrates and Products (Substrate)
44	Subunits
61	Synonyms
1	Systematic Name
16	Temperature Optimum [°C]
4	Temperature Range [°C]
6	Temperature Stability [°C]
52	Turnover Number [1/s]

KI Value

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KI Value on EC 1.13.11.4 - gentisate 1,2-dioxygenase

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Ki VALUE [mM]

INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

1.069

2,3-Dihydroxybenzoate

Rhodococcus opacus

W5U174

pH 8.5, 25°C

764240

1.13

2,4-Dihydroxybenzoate

Rhodococcus opacus

W5U174

pH 8.5, 25°C

764240

0.22

2,6-dihydroxybenzoate

Rhodococcus opacus

W5U174

pH 8.5, 25°C

764240

0.00145

4-Chlorocatechol

Rhodococcus opacus

W5U174

pH 8.5, 25°C

764240

0.0067

4-methylcatechol

Rhodococcus opacus

W5U174

pH 8.5, 25°C

764240

0.057

5-chlorosalicylate

Rhodococcus opacus

W5U174

pH 8.5, 25°C

764240

0.0449

catechol

Rhodococcus opacus

W5U174

pH 8.5, 25°C

764240

0.444

homogentisate

Rhodococcus opacus

W5U174

pH 8.5, 25°C

764240

0.33

Hydroxyquinol

Rhodococcus opacus

W5U174

pH 8.5, 25°C

764240

0.81

salicylate

Rhodococcus opacus

W5U174

pH 8.5, 25°C

764240