1.13.11.4: gentisate 1,2-dioxygenase

This is an abbreviated version!
For detailed information about gentisate 1,2-dioxygenase, go to the full flat file.

Word Map on EC 1.13.11.4

1.13.11.4

maleylpyruvate

protocatechuate

3-hydroxybenzoate

pseudaminobacter

salicylatoxidans

1-hydroxy-2-naphthoate

3,4-dioxygenase

monohydroxylated

fumarylpyruvate

isofunctional

5-hydroxylase

ring-fission

ring-cleaving

extradiol

bicupins

nocardioides

acidovorans

Reaction

2,5-Dihydroxybenzoate

+

O2

=

maleylpyruvate

Synonyms

2,5-dihydroxybenzoate dioxygenase, DsmD, EC 1.13.1.4, EC 1.99.2.4, eGDO, GDO, GDO-II, gdoA, GDOsp, GenH, gentisate dioxygenase, gentisate oxygenase, gentisate-1,2-dioxygenase, gentisic acid oxidase, gtdA-2, hbzE, Nagl1, Nagl2, Nagl3, NarI, oxygenase, gentisate 1,2-di-, P25X gentisate 1,2-dioxygenase, P35X gentisate 1,2-dioxygenase, salicylate 1,2-dioxygenase, SDO

ECTree

1 Oxidoreductases

1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)

1.13.11 With incorporation of two atoms of oxygen

1.13.11.4 gentisate 1,2-dioxygenase

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Results	in table
16	Activating Compound
1405	AA Sequence
2	Application
1	CAS Registry Number
24	Cloned(Commentary)
5	Crystallization (Commentary)
4	Expression
15	General Information
14	General Stability
79	Inhibitors
19	kcat/KM [mM/s]
10	Ki Value [mM]
117	KM Value [mM]
30	Metals/Ions
44	Molecular Weight [Da]
26	Natural Substrates/ Products (Substrates)
124	Organism
4	Oxidation Stability
9	Pathway
17	PDB ID
22	pH Optimum
2	pH Range
11	pH Stability
8	pI Value
90	Protein Variants
31	Purification (Commentary)
3	Reaction
3	Reaction Type
76	Reference
2	Renatured (Commentary)
8	Source Tissue
25	Specific Activity [micromol/min/mg]
21	Storage Stability
246	Substrates and Products (Substrate)
44	Subunits
61	Synonyms
1	Systematic Name
16	Temperature Optimum [°C]
4	Temperature Range [°C]
6	Temperature Stability [°C]
52	Turnover Number [1/s]

KCat KM Value

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KCat KM Value on EC 1.13.11.4 - gentisate 1,2-dioxygenase

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20.44 - 2310

2,5-Dihydroxybenzoate

show

1.7

3-aminosalicylate

Pseudaminobacter salicylatoxidans

pH 8.0, temperature not specified in the publication

3.6

3-bromosalicylate

Pseudaminobacter salicylatoxidans

pH 8.0, temperature not specified in the publication

286.1

3-Chlorogentisate

Rhizorhabdus dicambivorans

-

pH 7.4, 30°C

13.6

3-chlorosalicylate

Pseudaminobacter salicylatoxidans

pH 8.0, temperature not specified in the publication

7.1

3-hydroxysalicylate

Pseudaminobacter salicylatoxidans

pH 8.0, temperature not specified in the publication

25

3-methylsalicylate

Pseudaminobacter salicylatoxidans

pH 8.0, temperature not specified in the publication

8.1

4-chlorosalicylate

Pseudaminobacter salicylatoxidans

pH 8.0, temperature not specified in the publication

6.2

4-hydroxysalicylate

Pseudaminobacter salicylatoxidans

pH 8.0, temperature not specified in the publication

11

4-methylsalicylate

Pseudaminobacter salicylatoxidans

pH 8.0, temperature not specified in the publication

1.1 - 19.1

5-Aminosalicylate

show

6.2

5-chlorosalicylate

Pseudaminobacter salicylatoxidans

pH 8.0, temperature not specified in the publication

0.4 - 39.3

5-Fluorosalicylate

show

43

5-Methylsalicylate

Pseudaminobacter salicylatoxidans

pH 8.0, temperature not specified in the publication

28.4

gentisate

Pseudaminobacter salicylatoxidans

pH 8.0, temperature not specified in the publication

187.5

salicylate

Pseudaminobacter salicylatoxidans

pH 8.0, temperature not specified in the publication

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Release 2023.1 (January 2023)