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1.13.11.17: indole 2,3-dioxygenase

This is an abbreviated version!
For detailed information about indole 2,3-dioxygenase, go to the full flat file.

Word Map on EC 1.13.11.17

Reaction

indole
+
O2
=
2-formylaminobenzaldehyde

Synonyms

IDO, indole 2,3-dioxygenase, indole oxidase, indole:O2 oxidoreductase, indoleamine 2,3-dioxygenase, oxygenase, indole 2,3-di-

ECTree

     1 Oxidoreductases
         1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
             1.13.11 With incorporation of two atoms of oxygen
                1.13.11.17 indole 2,3-dioxygenase

Inhibitors

Inhibitors on EC 1.13.11.17 - indole 2,3-dioxygenase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2-mercaptoethanol
8-hydroxyquinoline
Atebrin
azide
CO
-
0.5 mM, 58% inhibition
Cu2+
-
1 mM, CuSO4, 25% inhibition
cyanide
diethyldithiocarbamate
Dithionite
dithiothreitol
-
0.0005 mM, 97% inhibition
iodoacetate
-
0.0005 mM, 19% inhibition
Neocuproine
-
0.001 mM, 92% inhibition
Salicylaldoxime