1.1.1.255: mannitol dehydrogenase

This is an abbreviated version, for detailed information about mannitol dehydrogenase, go to the full flat file.

Reaction

D-mannitol
+
NAD+
=
D-mannose
+
NADH
+
H+

Synonyms

mannitol 1-dehydrogenase, mannitol 1-oxidoreductase, mannitol:mannose 1-oxidoreductase, MTD, NAD-dependent mannitol dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.255 mannitol dehydrogenase

Reaction

Reaction on EC 1.1.1.255 - mannitol dehydrogenase

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REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
D-mannitol + NAD+ = D-mannose + NADH + H+
show the reaction diagram
The enzyme from Apium graveolens (celery) oxidizes alditols with a minimum requirement of 2R chirality at the carbon adjacent to the primary carbon undergoing the oxidation. The enzyme is specific for NAD+ and does not use NADP+
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