1.1.1.172: 2-oxoadipate reductase

This is an abbreviated version, for detailed information about 2-oxoadipate reductase, go to the full flat file.

Reaction

2-hydroxyadipate
+
NAD+
=
2-oxoadipate
+
NADH
+
H+

Synonyms

2-ketoadipate reductase, alpha-ketoadipate reductase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.172 2-oxoadipate reductase

Inhibitors

Inhibitors on EC 1.1.1.172 - 2-oxoadipate reductase

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INHIBITORS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
NADH
-
uncompetitive inhibition at high concentrations
oxalate
-
10% inhibition at 0.5 mM
p-chloromercuribenzoate
-
slight inhibition at 0.02 mM, combined with 0.26 mM SDS
SDS
-
slight inhibition at 0.26 mM, combined with 0.02 mM p-chloromercuribenzoate