1.1.1.165: 2-alkyn-1-ol dehydrogenase

This is an abbreviated version, for detailed information about 2-alkyn-1-ol dehydrogenase, go to the full flat file.

Reaction

2-butyne-1,4-diol
+
NAD+
=
4-Hydroxy-2-butynal
+
NADH
+
H+

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.165 2-alkyn-1-ol dehydrogenase

Substrates Products

Substrates Products on EC 1.1.1.165 - 2-alkyn-1-ol dehydrogenase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
1,2,4-butanetriol + NAD+
? + NADH
show the reaction diagram
1,2-butanediol + NAD+
1-hydroxybutan-2-one + NADH
show the reaction diagram
1,2-propanediol + NAD+
1-hydroxy-2-propanal + NADH
show the reaction diagram
1,4-butanediol + NAD+
1-hydroxy-4-butanal + NADH
show the reaction diagram
1,6-hexanediol + NAD+
1-hydroxy-6-hexanal + NADH
show the reaction diagram
-
low activity
-
?
1-butene-3-ol + NAD+
1-buten-3-one + NADH
show the reaction diagram
-
low activity
-
?
1-butyne-3-ol + NAD+
1-butyne-3-one + NADH
show the reaction diagram
-
very low activity
-
?
2-butene-1-ol + NAD+
2-butene-1-al + NADH
show the reaction diagram
-
cis-trans mixture, very low activity
-
?
2-butyne-1,4-diol + NAD+
4-hydroxybut-2-ynal + NADH
show the reaction diagram
-
-
-
?
2-butyne-1-ol + NAD+
2-butyn-1-al + NADH
show the reaction diagram
-
highest activity
-
?
2-propene-1-ol + NAD+
2-propene-1-al + NADH
show the reaction diagram
-
low activity
-
?
2-propyne-1-ol + NAD+
2-propyn-1-al + NADH
show the reaction diagram
-
-
-
?
3-butyne-1-ol + NAD+
3-butyn-1-al + NADH
show the reaction diagram
-
very low activity
-
?
n-propanol + NAD+
n-propanal + NADH
show the reaction diagram
trans-2-butene-1,4-diol + NAD+
? + NADH
show the reaction diagram
-
-
-
?