1.1.1.135: GDP-6-deoxy-D-talose 4-dehydrogenase

This is an abbreviated version, for detailed information about GDP-6-deoxy-D-talose 4-dehydrogenase, go to the full flat file.

Reaction

GDP-6-deoxy-alpha-D-talose
+
NAD(P)+
=
GDP-4-dehydro-alpha-D-rhamnose
+
NAD(P)H
+
H+

Synonyms

GDP-4-keto-rhamnose reductase, GDP-6-deoxy-D-talose dehydrogenase, guanosine diphospho-6-deoxy-D-talose dehydrogenase, HADH2

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.135 GDP-6-deoxy-D-talose 4-dehydrogenase

Engineering

Engineering on EC 1.1.1.135 - GDP-6-deoxy-D-talose 4-dehydrogenase

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ENGINEERING
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
L122C
missence mutation found in patient with inborn error of isoleucine degradation, almost complete loss of enzyme activity
R130C
missence mutation found in patient with inborn error of isoleucine degradation, almost complete loss of enzyme activity