1.1.1.126: 2-dehydro-3-deoxy-D-gluconate 6-dehydrogenase

This is an abbreviated version, for detailed information about 2-dehydro-3-deoxy-D-gluconate 6-dehydrogenase, go to the full flat file.

Reaction

2-dehydro-3-deoxy-D-gluconate
+
NADP+
=
(4S,5S)-4,5-dihydroxy-2,6-dioxohexanoate
+
NADPH
+
H+

Synonyms

2-keto-3-deoxy-D-gluconate dehydrogenase, 2-keto-3-deoxygluconate dehydrogenase, DDGDH, ketodeoxygluconate dehydrogenase, NAD-dependent 3-dehydro-2-deoxy-D-gluconate dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.126 2-dehydro-3-deoxy-D-gluconate 6-dehydrogenase

Purification

Purification on EC 1.1.1.126 - 2-dehydro-3-deoxy-D-gluconate 6-dehydrogenase

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Purification/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
Super Q Toyopearl 650M column chromatography, Resource Q column chromatography, Bio-Scale CHT20-I column chromatography, and Superdex 75 gel filtration
-
to homogeneity, chromatography techniques
-