Reaction catalyzed by 3'-phosphate/5'-hydroxy nucleic acid ligase (6.5.1.8)

		+		5\'-hydroxy-(ribonucleotide)m	=			+
	(ribonucleotide)n-3'-(5'-diphosphoguanosine)	+		5'-hydroxy-(ribonucleotide)m	=		(ribonucleotide)n+m	+		GMP