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8-Bromoadenosine 5'-triphosphate + (ribonucleotide)n + (ribonucleotide)m = 8-Bromoadenosine monophosphate + (ribonucleotide)n+m
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8-Sulfoadenosine 5'-triphosphate + (ribonucleotide)n + (ribonucleotide)m = 8-Sulfoadenosinemonophosphate + phosphate + (ribonucleotide)n+m
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653234, 1983, 653369, 653679, 654015, 652246, 1997, 650172, 653368, 653882, 653392, 653915, 1984, 1987, 1988, 1991, 1995, 1994, 1993, 649963, 652387, 1985, 1999, 652429, , 1996, 650982, 651858, 653217, 653869, 653889, 1910, 1986, 1989, 1990, 1992, 1998, 2000, 2001, 650653, 651051, 651061
ATP + (ribonucleotide)n + (ribonucleotide)m = AMP + diphosphate + (ribonucleotide)n+m
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ATP + (ribonucleotide)n-3'-hydroxyl + 5'-phospho-(ribonucleotide)m = (ribonucleotide)n+m + AMP + diphosphate
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dATP + (ribonucleotide)n + (ribonucleotide)m = dAMP + phosphate + (ribonucleotide)n+m
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ITP + (ribonucleotide)n + (ribonucleotide)m = IMP + phosphate + (ribonucleotide)n+m
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(ribonucleotide)n-2',3'-cyclophosphate + 5'-hydroxy-(ribonucleotide)m + ATP + H2O = (ribonucleotide)n+m + AMP + diphosphate
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(ribonucleotide)n-2',3'-cyclophosphate + 5'-hydroxy-(ribonucleotide)m + CTP + H2O = (ribonucleotide)n+m + CMP + diphosphate
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(ribonucleotide)n-2',3'-cyclophosphate + 5'-hydroxy-(ribonucleotide)m + GTP + H2O = (ribonucleotide)n+m + GMP + diphosphate
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(ribonucleotide)n-2',3'-cyclophosphate + 5'-hydroxy-(ribonucleotide)m + UTP + H2O = (ribonucleotide)n+m + UMP + diphosphate
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(ribonucleotide)n-2',3'-cyclophosphate + 5'-hydroxy-(ribonucleotide)m = (ribonucleotide)n+m
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(ribonucleotide)n-3'-(5'-diphosphoguanosine) + 5'-hydroxy-(ribonucleotide)m = (ribonucleotide)n+m + GMP
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(ribonucleotide)n-3'-phosphate + 5'-hydroxy-(ribonucleotide)m + 2-aminopurine-riboside-5'-triphosphate = (ribonucleotide)n+m + 2-aminopurine-riboside-5'-monophosphate + diphosphate
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(ribonucleotide)n-3'-phosphate + 5'-hydroxy-(ribonucleotide)m + 2-mercaptopurine-riboside-5'-triphosphate = (ribonucleotide)n+m + 2-mercaptopurine-riboside-5'-monophosphate + diphosphate
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(ribonucleotide)n-3'-phosphate + 5'-hydroxy-(ribonucleotide)m + 6-chloropurine-riboside-5'-triphosphate = (ribonucleotide)n+m + 6-chloropurine-riboside-5'-monophosphate + diphosphate
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(ribonucleotide)n-3'-phosphate + 5'-hydroxy-(ribonucleotide)m + 6-O-methylguanosine triphosphate = (ribonucleotide)n+m + 6-O-methylguanosine phosphate + diphosphate
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(ribonucleotide)n-3'-phosphate + 5'-hydroxy-(ribonucleotide)m + ATP = (ribonucleotide)n+m + AMP + diphosphate
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-
(ribonucleotide)n-3'-phosphate + 5'-hydroxy-(ribonucleotide)m + CTP = (ribonucleotide)n+m + CMP + diphosphate
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-
(ribonucleotide)n-3'-phosphate + 5'-hydroxy-(ribonucleotide)m + GTP = (ribonucleotide)n+m + GMP + diphosphate
-
-
(ribonucleotide)n-3'-phosphate + 5'-hydroxy-(ribonucleotide)m + ITP = (ribonucleotide)n+m + IMP + diphosphate
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-
(ribonucleotide)n-3'-phosphate + 5'-hydroxy-(ribonucleotide)m + UTP = (ribonucleotide)n+m + UMP + diphosphate
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-
(ribonucleotide)n-3'-phosphate + 5'-phospho-(ribonucleotide)m + GTP = (ribonucleotide)n+m + GMP + diphosphate
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DNA and RNA ligases (EC 6.5.1.1, EC 6.5.1.2, and EC 6.5.1.3)
1993
Maunders, M.J.
Methods Mol. Biol.
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213-230
Purification of wheat germ RNA ligase. I. Characterization of a ligase-associated 5'-hydroxyl polynucleotide kinase activity
1986
Pick, L.; Hurwitz, J.
J. Biol. Chem.
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Purification of wheat germ RNA ligase. II. Mechanism of action of wheat germ RNA ligase
1986
Pick, L.; Furneaux, H.; Hurwitz, J.
J. Biol. Chem.
261
6694-6704
Isolation and characterization of an RNA ligase from HeLa cells
1985
Perkins, K.K.; Furneaux, H.; Hurwitz, J.
Proc. Natl. Acad. Sci. USA
82
684-688
Sequence and cloning of bacteriophage T4 gene 63 encoding RNA ligase and tail fibre attachment activities
1984
Rand, K.N.; Gait, M.J.
EMBO J.
3
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Isolation and characterization of RNA ligase from wheat germ
1983
Furneaux, H.; Pick, L.; Hurwitz, J.
Proc. Natl. Acad. Sci. USA
80
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An RNA ligase from wheat germ which participates in transfer RNA splicing in vitro
1983
Gegenheimer, P.; Gabius, H.J.; Peebles, C.L.; Abelson, J.
J. Biol. Chem.
258
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Purification of T4 RNA ligase by dextran blue-Sepharose 4B affinity chromatography
1982
Mei-Hao, H.; Wang, A.; Hui-Fen, H.
Anal. Biochem.
125
1-5
A new procedure for the simultaneous large-scale purification of bacteriophage-T4-induced polynucleotide kinase, DNA ligase, RNA ligase and DNA polymerase
1981
Dolganov, G.M.; Chestukhin, A.V.; Shemyakin, M.
Eur. J. Biochem.
114
247-254
Formation of a 2'-phosphomonoester, 3',5'-phosphodiester linkage by a novel RNA ligase in wheat germ
1981
Konarska, M.; Filipowicz, W.; Domdey, H.; Gross, H.J.
Nature
293
112-116
The Purification of nuclease-free T4-RNA ligase
1979
Moseman McCoy, M.I.; Lubben, T.H.; Gumport, R.I.
Biochim. Biophys. Acta
562
149-161
Purification of T4 RNA ligase by 2',5'-ADP Sepharose chromatography
1979
Sugiura, M.; Suzuki, M.; Ohtsuka, E.; Nishikawa, S.; Uemura, H.; Ikehara, M.
FEBS Lett.
97
73-76
Purification and properties of bacteriophage T4-induced RNA ligase
1976
Last, J.A.; Anderson, W.F.
Arch. Biochem. Biophys.
174
167-176
Purification and properties of bacteriophage T4-induced RNA ligase
1972
Silber, R.; Malathi, V.G.; Hurwitz, J.
Proc. Natl. Acad. Sci. USA
69
3009-3013
Purification of a functional enzymatic editing complex from Trypanosoma brucei mitochondria
1997
Rusche, L.N.; Cruz-Reyes, J.; Piller, K.J.; Sollner-Webb, B.
EMBO J.
16
4069-4081
The Leishmania kinetoplast-mitochondrion contains terminal uridylyltransferase and RNA ligase activities
1989
Bakalara, N.; Simpson, A.M.; Simpson, L.
J. Biol. Chem.
264
18679-18686
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Inhibition of the first stage of RNA ligase reaction by ATP analogues
1991
Juodka, B.; Labeikyte, D.
Nucleosides Nucleotides
10
367-370
Purification and characterization of wheat germ RNA ligase and associated activities
1990
Pick, L.; Furneaux, H.M.; Hurwitz, J.
Methods Enzymol.
181
480-499
In vitro selection of optimal substrates for T4 RNA ligase
1993
Harada, K.; Orgel, L.E.
Proc. Natl. Acad. Sci. USA
90
1576-1579
Substrate specificity of T4 RNA-ligase: the role of a purine nucleotide base in forming a covalent AMP-RNA ligase complex
1993
Iuoda, B.A.; Labeikite, D.; Sasnauskene, S.I.
Biokhimiia
58
857-865
Kinetic framework for ligation by an efficient RNA ligase ribozyme
2000
Bergman, N.H.; Johnston, W.K.; Bartel, D.P.
Biochemistry
39
3115-3123
Metal ion requirements for structure and catalysis of an RNA ligase ribozyme
2002
Glasner, M.E.; Bergman, N.H.; Bartel, D.P.
Biochemistry
41
8103-8112
Purification of histidine-tagged T4 RNA ligase from E. coli
2002
Wang, Q.S.; Unrau, P.J.
Biotechniques
33
1256-1260
Roles for ligases in the RNA editing complex of Trypanosoma brucei: band IV is needed for U-deletion and RNA repair
2001
Huang, C.E.; Cruz-Reyes, J.; Zhelonkina, A.G.; O'Hearn, S.; Wirtz, E.; Sollner-Webb, B.
EMBO J.
20
4694-4703
T4 RNA ligase catalyzes the synthesis of dinucleoside polyphosphates
1999
Atencia, E.A.; Madrid, O.; Gunther Sillero, M.A.; Sillero, A.
Eur. J. Biochem.
261
802-811
Several dinucleoside polyphosphates are acceptor substrates in the T4 RNA ligase catalyzed reaction
2000
Atencia, E.A.; Montes, M.; Gunther Sillero, M.A.; Sillero, A.
Eur. J. Biochem.
267
1707-1714
Trypanosoma brucei RNA editing. A full round of uridylate insertional editing in vitro mediated by endonuclease and RNA ligase
1996
Piller, K.J.; Rusche, L.N.; Sollner-Webb, B.
J. Biol. Chem.
271
4613-4619
Kinetic mechanism of the Mg2+-dependent nucleotidyl transfer catalyzed by T4 DNA and RNA ligases
2002
Cherepanov, A.V.; de Vries, S.
J. Biol. Chem.
277
1695-1704
Structure-function analysis of T4 RNA ligase 2
2003
Yin, S.; Ho, C.K.; Shuman, S.
J. Biol. Chem.
278
17601-17608
Mutational analysis of bacteriophage T4 RNA ligase 1. Different functional groups are required for the nucleotidyl transfer and phosphodiester bond formation steps of the ligation reaction
2003
Wang, L.K.; Ho, C.K.; Pei, Y.; Shuman, S.
J. Biol. Chem.
278
29454-29462
Distinct functions of two RNA ligases in active Trypanosoma brucei RNA editing complexes
2002
Cruz-Reyes, J.; Zhelonkina, A.G.; Huang, C.E.; Sollner-Webb, B.
Mol. Cell. Biol.
22
4652-4660
Y-ligation: an efficient method for ligating single-stranded DNAs and RNAs with T4 RNA ligase
1998
Nishigaki, K.; Taguchi, K.; Kinoshita, Y.; Aita, T.; Husimi, Y.
Mol. Divers.
4
187-190
The secondary structure and sequence optimization of an RNA ligase ribozyme
1995
Ekland, E.H.; Bartel, D.P.
Nucleic Acids Res.
23
3231-3238
Oligoribonucleotide circularization by 'template-mediated' ligation with T4 RNA ligase: synthesis of circular hammerhead ribozymes
1998
Wang, L.; Ruffner, D.E.
Nucleic Acids Res.
26
2502-2504
Discovery and characterization of a thermostable bacteriophage RNA ligase homologous to T4 RNA ligase 1
2003
Blondal, T.; Hjorleifsdottir, S.H.; Fridjonsson, O.F.; Aevarsson, A.; Skirnisdottir, S.; Hermannsdottir, A.G.; Hreggvidsson, G.O.; Smith, A.V.; Kristjansson, J.K.
Nucleic Acids Res.
31
7247-7254
Bacteriophage T4 RNA ligase 2 (gp24.1) exemplifies a family of RNA ligases found in all phylogenetic domains
2002
Ho, C.K.; Shuman, S.
Proc. Natl. Acad. Sci. USA
99
12709-12714
Identification of candidate mitochondrial RNA editing ligases from Trypanosoma brucei
2001
McManus, M.T.; Shimamura, M.; Grams, J.; Hajduk, S.L.
RNA
7
167-175
Structurally complex and highly active RNA ligases derived from random RNA sequences
1995
Ekland, E.H.; Szostak, J.W.; Bartel, D.P.
Science
269
364-370
An RNA ligase essential for RNA editing and survival of the bloodstream form of Trypanosoma brucei
2001
Schnaufer, A.; Panigrahi, A.K.; Panicucci, B.; Igo, R.P., Jr.; Wirtz, E.; Salavati, R.; Stuart, K.
Science
291
2159-2162
Structure and mechanism of RNA ligase
2004
Ho, C.K.; Wang, L.K.; Lima, C.D.; Shuman, S.
Structure
12
327-339
Characterization of bacteriophage KVP40 and T4 RNA ligase 2
2004
Yin, S.; Kiong Ho, C.; Miller, E.S.; Shuman, S.
Virology
319
141-151
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