Sequence of GALT1_MOUSE
EC Number:2.4.1.41
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
UDP-N-acetyl-alpha-D-galactosamine + [protein]-L-serine = UDP + [protein]-3-O-(N-acetyl-alpha-D-galactosaminyl)-L-serine
Other sequences found for EC No. 2.4.1.41
General information:
Sequence
0 MRKFAYCKVV LATSLVWVLL DMFLLLYFSE CNKCEEKQER GLPAGDVLEL VQKPHEGPGE
60 MGKPVVIPKE DQEKMKEMFK INQFNLMASE MIALNRSLPD VRLEGCKTKV YPDNLPTTSV
120 VIVFHNEAWS TLLRTVHSVI NRSPRHMIEE IVLVDDASER DFLKRPLESY VKKLKVPVHV
180 IRMEQRSGLI RARLKGAAVS RGQVITFLDA HCECTAGWLE PLLARIKHDR RTVVCPIIDV
240 ISDDTFEYMA GSDMTYGGFN WKLNFRWYPV PQREMDRRKG DRTLPVRTPT MAGGLFSIDR
300 DYFQEIGTYD AGMDIWGGEN LEISFRIWQC GGTLEIVTCS HVGHVFRKAT PYTFPGGTGQ
360 IINKNNRRLA EVWMDEFKNF FYIISPGVTK VDYGDISSRL GLRRKLQCKP FSWYLENIYP
420 DSQIPRHYFS LGEIRNVETN QCLDNMARKE NEKVGIFNCH GMGGNQVFSY TANKEIRTDD
480 LCLDVSKLNG PVTMLKCHHL KGNQLWEYDP VKLTLQHVNS NQCLDKATEE DSQVPSIRDC
540 TGSRSQQWLL RNVTLPEIF
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
420666
Hagen F.K.,Ten Hagen K.G.,Beres T.M.,Balys M.M.,VanWuyckhuyse B.C.,Tabak L.A.
cDNA cloning and expression of a novel UDP-N-acetyl-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase.
J. Biol. Chem.
272
13843-13848
1997
420667
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
420668
Hagen F.K.,Hazes B.,Raffo R.,deSa D.,Tabak L.A.
Structure-function analysis of the UDP-N-acetyl-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase. Essential residues lie in a predicted active site cleft resembling a lactose repressor fold.
J. Biol. Chem.
274
6797-6803
1999
420669
Young W.W. Jr.,Holcomb D.R.,Ten Hagen K.G.,Tabak L.A.
Expression of UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase isoforms in murine tissues determined by real-time PCR: a new view of a large family.
Glycobiology
13
549-557
2003
420670
Huttlin E.L.,Jedrychowski M.P.,Elias J.E.,Goswami T.,Rad R.,Beausoleil S.A.,Villen J.,Haas W.,Sowa M.E.,Gygi S.P.
A tissue-specific atlas of mouse protein phosphorylation and expression.
Cell
143
1174-1189
2010
420671
Fritz T.A.,Hurley J.H.,Trinh L.B.,Shiloach J.,Tabak L.A.
The beginnings of mucin biosynthesis: the crystal structure of UDP-GalNAc:polypeptide alpha-N-acetylgalactosaminyltransferase-T1.
Proc. Natl. Acad. Sci. U.S.A.
101
15307-15312
2004
