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Sequence of COABC_MYCTU

EC Number:4.1.1.36

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
phosphopantothenoylcysteine decarboxylase
P9WNZ1
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
418
43577
Reaction
N-[(R)-4'-phosphopantothenoyl]-L-cysteine = pantotheine 4'-phosphate + CO2
Other sequences found for EC No. 4.1.1.36

General information:

Sequence
show sequence in fasta format
  0 MVDHKRIPKQ VIVGVSGGIA AYKACTVVRQ LTEASHRVRV IPTESALRFV GAATFEALSG
 60 EPVCTDVFAD VPAVPHVHLG QQADLVVVAP ATADLLARAA AGRADDLLTA TLLTARCPVL
120 FAPAMHTEMW LHPATVDNVA TLRRRGAVVL EPATGRLTGA DSGAGRLPEA EEITTLAQLL
180 LERHDALPYD LAGRKLLVTA GGTREPIDPV RFIGNRSSGK QGYAVARVAA QRGADVTLIA
240 GHTAGLVDPA GVEVVHVSSA QQLADAVSKH APTADVLVMA AAVADFRPAQ VATAKIKKGV
300 EGPPTIELLR NDDVLAGVVR ARAHGQLPNM RAIVGFAAET GDANGDVLFH ARAKLRRKGC
360 DLLVVNAVGE GRAFEVDSND GWLLASDGTE SALQHGSKTL MASRIVDAIV TFLAGCSS
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
403411
Cole S.T.,Brosch R.,Parkhill J.,Garnier T.,Churcher C.M.,Harris D.E.,Gordon S.V.,Eiglmeier K.,Gas S.,Barry C.E. III,Tekaia F.,Badcock K.,Basham D.,Brown D.,Chillingworth T.,Connor R.,Davies R.M.,Devlin K.,Feltwell T.,Gentles S.,Hamlin N.,Holroyd S.,Hornsby T.,Jagels K.,Krogh A.,McLean J.,Moule S.,Murphy L.D.,Oliver S.,Osborne J.,Quail M.A.,Rajandream M.A.,Rogers J.,Rutter S.,Seeger K.,Skelton S.,Squares S.,Squares R.,Sulston J.E.,Taylor K.,Whitehead S.,Barrell B.G.
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
Nature
393
537-544
1998
403412
Raman K.,Yeturu K.,Chandra N.
targetTB: a target identification pipeline for Mycobacterium tuberculosis through an interactome, reactome and genome-scale structural analysis.
BMC Syst. Biol.
2
109-109
2008
403413
Kelkar D.S.,Kumar D.,Kumar P.,Balakrishnan L.,Muthusamy B.,Yadav A.K.,Shrivastava P.,Marimuthu A.,Anand S.,Sundaram H.,Kingsbury R.,Harsha H.C.,Nair B.,Prasad T.S.,Chauhan D.S.,Katoch K.,Katoch V.M.,Kumar P.,Chaerkady R.,Ramachandran S.,Dash D.,Pandey A.
Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.
Mol. Cell. Proteomics
10
0-0
2011
403414
Evans J.C.,Trujillo C.,Wang Z.,Eoh H.,Ehrt S.,Schnappinger D.,Boshoff H.I.,Rhee K.Y.,Barry C.E. III,Mizrahi V.
Validation of CoaBC as a bactericidal target in the coenzyme A pathway of Mycobacterium tuberculosis.
ACS Infect. Dis.
2
958-968
2016
403415
Mendes V.,Green S.R.,Evans J.C.,Hess J.,Blaszczyk M.,Spry C.,Bryant O.,Cory-Wright J.,Chan D.S.,Torres P.H.M.,Wang Z.,Nahiyaan N.,O'Neill S.,Damerow S.,Post J.,Bayliss T.,Lynch S.L.,Coyne A.G.,Ray P.C.,Abell C.,Rhee K.Y.,Boshoff H.I.M.,Barry C.E. III,Mizrahi V.,Wyatt P.G.,Blundell T.L.
Inhibiting Mycobacterium tuberculosis CoaBC by targeting an allosteric site.
Nat. Commun.
12
143-143
2021