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Sequence of UCHL1_RAT

EC Number:3.4.19.12

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
ubiquitinyl hydrolase 1
Q00981
Rattus norvegicus
223
24838
Reaction
Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal)
Other sequences found for EC No. 3.4.19.12

General information:

Sequence
show sequence in fasta format
  0 MQLKPMEINP EMLNKVLAKL GVAGQWRFAD VLGLEEETLG SVPSPACALL LLFPLTAQHE
 60 NFRKKQIEEL KGQEVSPKVY FMKQTIGNSC GTIGLIHAVA NNQDKLEFED GSVLKQFLSE
120 TEKLSPEDRA KCFEKNEAIQ AAHDSVAQEG QCRVDDKVNF HFILFNNVDG HLYELDGRMP
180 FPVNHGASSE DSLLQDAAKV CREFTEREQG EVRFSAVALC KAA
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
372696
Kajimoto Y.,Hashimoto T.,Shirai Y.,Nishino N.,Kuno T.,Tanaka C.
cDNA cloning and tissue distribution of a rat ubiquitin carboxyl-terminal hydrolase PGP9.5.
J. Biochem.
112
28-32
1992
372697
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
372699
Cole R.N.,Hart G.W.
Cytosolic O-glycosylation is abundant in nerve terminals.
J. Neurochem.
79
1080-1089
2001
372700
Liu Y.,Fallon L.,Lashuel H.A.,Liu Z.,Lansbury P.T. Jr.
The UCH-L1 gene encodes two opposing enzymatic activities that affect alpha-synuclein degradation and Parkinson's disease susceptibility.
Cell
111
209-218
2002
372701
Lundby A.,Secher A.,Lage K.,Nordsborg N.B.,Dmytriyev A.,Lundby C.,Olsen J.V.
Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.
Nat. Commun.
3
876-876
2012