Sequence of PEPA_ASPFU
EC Number:3.4.23.18
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Aspergillopepsin I
P41748
Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)
395
41613
Reaction
hydrolysis of proteins with broad specificity. Generally favours hydrophobic residues in P1 and P1', but also accepts Lys in P1, which leads to activation of trypsinogen. Does not clot milk
Other sequences found for EC No. 3.4.23.18
General information:
Sequence
0 MVVFSKVTAV VVGLSTIVSA VPVVQPRKGF TINQVARPVT NKKTVNLPAV YANALTKYGG
60 TVPDSVKAAA SSGSAVTTPE QYDSEYLTPV KVGGTTLNLD FDTGSADLWV FSSELSASQS
120 SGHAIYKPSA NAQKLNGYTW KIQYGDGSSA SGDVYKDTVT VGGVTAQSQA VEAASHISSQ
180 FVQDKDNDGL LGLAFSSINT VSPRPQTTFF DTVKSQLDSP LFAVTLKYHA PGTYDFGYID
240 NSKFQGELTY TDVDSSQGFW MFTADGYGVG NGAPNSNSIS GIADTGTTLL LLDDSVVADY
300 YRQVSGAKNS NQYGGYVFPC STKLPSFTTV IGGYNAVVPG EYINYAPVTD GSSTCYGGIQ
360 SNSGLGFSIF GDIFLKSQYV VFDSQGPRLG FAPQA
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
332485
Lee J.D.,Kolattukudy P.E.
Molecular cloning of the cDNA and gene for an elastinolytic aspartic proteinase from Aspergillus fumigatus and evidence of its secretion by the fungus during invasion of the host lung.
Infect. Immun.
63
3796-3803
1995
332486
Reichard U.,Monod M.,Ruechel R.
Molecular cloning and sequencing of the gene encoding an extracellular aspartic proteinase from Aspergillus fumigatus.
FEMS Microbiol. Lett.
130
69-74
1995
332487
Nierman W.C.,Pain A.,Anderson M.J.,Wortman J.R.,Kim H.S.,Arroyo J.,Berriman M.,Abe K.,Archer D.B.,Bermejo C.,Bennett J.W.,Bowyer P.,Chen D.,Collins M.,Coulsen R.,Davies R.,Dyer P.S.,Farman M.L.,Fedorova N.,Fedorova N.D.,Feldblyum T.V.,Fischer R.,Fosker N.,Fraser A.,Garcia J.L.,Garcia M.J.,Goble A.,Goldman G.H.,Gomi K.,Griffith-Jones S.,Gwilliam R.,Haas B.J.,Haas H.,Harris D.E.,Horiuchi H.,Huang J.,Humphray S.,Jimenez J.,Keller N.,Khouri H.,Kitamoto K.,Kobayashi T.,Konzack S.,Kulkarni R.,Kumagai T.,Lafton A.,Latge J.-P.,Li W.,Lord A.,Lu C.,Majoros W.H.,May G.S.,Miller B.L.,Mohamoud Y.,Molina M.,Monod M.,Mouyna I.,Mulligan S.,Murphy L.D.,O'Neil S.,Paulsen I.,Penalva M.A.,Pertea M.,Price C.,Pritchard B.L.,Quail M.A.,Rabbinowitsch E.,Rawlins N.,Rajandream M.A.,Reichard U.,Renauld H.,Robson G.D.,Rodriguez de Cordoba S.,Rodriguez-Pena J.M.,Ronning C.M.,Rutter S.,Salzberg S.L.,Sanchez M.,Sanchez-Ferrero J.C.,Saunders D.,Seeger K.,Squares R.,Squares S.,Takeuchi M.,Tekaia F.,Turner G.,Vazquez de Aldana C.R.,Weidman J.,White O.,Woodward J.R.,Yu J.-H.,Fraser C.M.,Galagan J.E.,Asai K.,Machida M.,Hall N.,Barrell B.G.,Denning D.W.
Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus.
Nature
438
1151-1156
2005
