Sequence of KLK3_HUMAN
EC Number:3.4.21.77
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
Preferential cleavage: -Tyr-/-
Other sequences found for EC No. 3.4.21.77
General information:
Sequence
0 MWVPVVFLTL SVTWIGAAPL ILSRIVGGWE CEKHSQPWQV LVASRGRAVC GGVLVHPQWV
60 LTAAHCIRNK SVILLGRHSL FHPEDTGQVF QVSHSFPHPL YDMSLLKNRF LRPGDDSSHD
120 LMLLRLSEPA ELTDAVKVMD LPTQEPALGT TCYASGWGSI EPEEFLTPKK LQCVDLHVIS
180 NDVCAQVHPQ KVTKFMLCAG RWTGGKSTCS GDSGGPLVCN GVLQGITSWG SEPCALPERP
240 SLYTKVVHYR KWIKDTIVAN P
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
310749
Lundwall A.,Lilja H.
Molecular cloning of human prostate specific antigen cDNA.
FEBS Lett.
214
317-322
1987
310750
Digby M.R.,Zhang X.Y.,Richard R.I.
Human prostate specific antigen (PSA) gene: structure and linkage to the kallikrein-like gene, hGK-1.
Nucleic Acids Res.
17
2137-2137
1989
310751
Klobeck H.-G.,Combriato G.,Schulz P.,Arbusow V.,Fittler F.
Genomic sequence of human prostate specific antigen (PSA).
Nucleic Acids Res.
17
3981-3981
1989
310752
Lundwall A.
Characterization of the gene for prostate-specific antigen, a human glandular kallikrein.
Biochem. Biophys. Res. Commun.
161
1151-1159
1989
310753
Henttu P.,Vihko P.
cDNA coding for the entire human prostate specific antigen shows high homologies to the human tissue kallikrein genes.
Biochem. Biophys. Res. Commun.
160
903-910
1989
310754
Riegman P.H.J.,Vlietstra R.J.,van der Korput J.A.G.M.,Romijn J.C.,Trapman J.
Characterization of the prostate-specific antigen gene: a novel human kallikrein-like gene.
Biochem. Biophys. Res. Commun.
159
95-102
1989
310755
Baffa R.,Moreno J.G.,Monne M.,Veronese M.L.,Gomella L.G.
A comparative analysis of prostate-specific antigen gene sequence in benign and malignant prostate tissue.
Urology
47
795-800
1996
310756
Gan L.,Lee I.,Smith R.,Argonza-Barrett R.,Lei H.,McCuaig J.,Moss P.,Paeper B.,Wang K.
Sequencing and expression analysis of the serine protease gene cluster located in chromosome 19q13 region.
Gene
257
119-130
2000
310759
Grimwood J.,Gordon L.A.,Olsen A.S.,Terry A.,Schmutz J.,Lamerdin J.E.,Hellsten U.,Goodstein D.,Couronne O.,Tran-Gyamfi M.,Aerts A.,Altherr M.,Ashworth L.,Bajorek E.,Black S.,Branscomb E.,Caenepeel S.,Carrano A.V.,Caoile C.,Chan Y.M.,Christensen M.,Cleland C.A.,Copeland A.,Dalin E.,Dehal P.,Denys M.,Detter J.C.,Escobar J.,Flowers D.,Fotopulos D.,Garcia C.,Georgescu A.M.,Glavina T.,Gomez M.,Gonzales E.,Groza M.,Hammon N.,Hawkins T.,Haydu L.,Ho I.,Huang W.,Israni S.,Jett J.,Kadner K.,Kimball H.,Kobayashi A.,Larionov V.,Leem S.-H.,Lopez F.,Lou Y.,Lowry S.,Malfatti S.,Martinez D.,McCready P.M.,Medina C.,Morgan J.,Nelson K.,Nolan M.,Ovcharenko I.,Pitluck S.,Pollard M.,Popkie A.P.,Predki P.,Quan G.,Ramirez L.,Rash S.,Retterer J.,Rodriguez A.,Rogers S.,Salamov A.,Salazar A.,She X.,Smith D.,Slezak T.,Solovyev V.,Thayer N.,Tice H.,Tsai M.,Ustaszewska A.,Vo N.,Wagner M.,Wheeler J.,Wu K.,Xie G.,Yang J.,Dubchak I.,Furey T.S.,DeJong P.,Dickson M.,Gordon D.,Eichler E.E.,Pennacchio L.A.,Richardson P.,Stubbs L.,Rokhsar D.S.,Myers R.M.,Rubin E.M.,Lucas S.M.
The DNA sequence and biology of human chromosome 19.
Nature
428
529-535
2004
310761
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
310762
Monne M.,Croce C.M.,Yu H.,Diamandis E.P.
Molecular characterization of prostate-specific antigen messenger RNA expressed in breast tumors.
Cancer Res.
54
6344-6347
1994
310763
Schulz P.,Stucka R.,Feldmann H.,Combriato G.,Klobeck H.-G.,Fittler F.
Sequence of a cDNA clone encompassing the complete mature human prostate specific antigen (PSA) and an unspliced leader sequence.
Nucleic Acids Res.
16
6226-6226
1988
310764
Watt K.W.K.,Lee P.J.,M'Timkulu T.,Chan W.P.,Loor R.
Human prostate-specific antigen: structural and functional similarity with serine proteases.
Proc. Natl. Acad. Sci. U.S.A.
83
3166-3170
1986
310765
Schaller J.,Akiyama K.,Tsuda R.,Hara M.,Marti T.,Rickli E.E.
Isolation, characterization and amino-acid sequence of gamma-seminoprotein, a glycoprotein from human seminal plasma.
Eur. J. Biochem.
170
111-120
1987
310766
Zhang Z.,Henzel W.J.
Signal peptide prediction based on analysis of experimentally verified cleavage sites.
Protein Sci.
13
2819-2824
2004
310767
Vegvari A.,Sjodin K.,Rezeli M.,Malm J.,Lilja H.,Laurell T.,Marko-Varga G.
Identification of a novel proteoform of prostate specific antigen (SNP-L132I) in clinical samples by multiple reaction monitoring.
Mol. Cell. Proteomics
12
2761-2773
2013
310768
Espana F.,Gilabert J.,Estelles A.,Romeu A.,Aznar J.,Cabo A.
Functionally active protein C inhibitor/plasminogen activator inhibitor-3 (PCI/PAI-3) is secreted in seminal vesicles, occurs at high concentrations in human seminal plasma and complexes with prostate-specific antigen.
Thromb. Res.
64
309-320
1991
310769
Villoutreix B.O.,Getzoff E.D.,Griffin J.H.
A structural model for the prostate disease marker, human prostate-specific antigen.
Protein Sci.
3
2033-2044
1994
310770
Coombs G.S.,Bergstrom R.C.,Pellequer J.L.,Baker S.I.,Navre M.,Smith M.M.,Tainer J.A.,Madison E.L.,Corey D.R.
Substrate specificity of prostate-specific antigen (PSA).
Chem. Biol.
5
475-488
1998
310771
Menez R.,Michel S.,Muller B.H.,Bossus M.,Ducancel F.,Jolivet-Reynaud C.,Stura E.A.
Crystal structure of a ternary complex between human prostate-specific antigen, its substrate acyl intermediate and an activating antibody.
J. Mol. Biol.
376
1021-1033
2008
