Sequence of HPXO_KLEP7
EC Number:1.14.13.113
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
FAD-dependent urate hydroxylase
A6T923
Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)
384
42107
Reaction
urate + NADH + H+ + O2 = 5-hydroxyisourate + NAD+ + H2O
Other sequences found for EC No. 1.14.13.113
General information:
Sequence
0 MKAIVIGAGI GGLSAAVALK QSGIDCDVYE AVKEIKPVGA AISVWPNGVK CMAHLGMGDI
60 METFGGPLRR MAYRDFRSGE NMTQFSLAPL IERTGSRPCP VSRAELQREM LDYWGRDSVQ
120 FGKRVTRCEE DADGVTVWFT DGSSASGDLL IAADGSHSAL RPWVLGFTPQ RRYAGYVNWN
180 GLVEIDEALA PGDQWTTFVG EGKRVSLMPV SAGRFYFFFD VPLPAGLAED RDTLRADLSR
240 YFAGWAPPVQ KLIAALDPQT TNRIEIHDIE PFSRLVRGRV ALLGDAGHST TPDIGQGGCA
300 AMEDAVVLGA VFRQTRDIAA ALREYEAQRC DRVRDLVLKA RKRCDITHGK DMQLTEAWYQ
360 ELREETGERI INGMCDTILS GPLG
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
303767
O'Leary S.E.,Hicks K.A.,Ealick S.E.,Begley T.P.
Biochemical characterization of the HpxO enzyme from Klebsiella pneumoniae, a novel FAD-dependent urate oxidase.
Biochemistry
48
3033-3035
2009
303768
Hicks K.A.,O'Leary S.E.,Begley T.P.,Ealick S.E.
Structural and mechanistic studies of HpxO, a novel flavin adenine dinucleotide-dependent urate oxidase from Klebsiella pneumoniae.
Biochemistry
52
477-487
2013
