Any feedback?
Please rate this page
(sequences.php)
(0/150)

BRENDA support

Sequence of END3_ECOLI

EC Number:4.2.99.18

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
DNA-(apurinic or apyrimidinic site) lyase
P0AB83
Escherichia coli (strain K12)
211
23562
Reaction
the C-O-P bond 3' to the apurinic or apyrimidinic site in DNA is broken by a beta-elimination reaction, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Other sequences found for EC No. 4.2.99.18

General information:

Sequence
show sequence in fasta format
  0 MNKAKRLEIL TRLRENNPHP TTELNFSSPF ELLIAVLLSA QATDVSVNKA TAKLYPVANT
 60 PAAMLELGVE GVKTYIKTIG LYNSKAENII KTCRILLEQH NGEVPEDRAA LEALPGVGRK
120 TANVVLNTAF GWPTIAVDTH IFRVCNRTQF APGKNVEQVE EKLLKVVPAE FKVDCHHWLI
180 LHGRYTCIAR KPRCGSCIIE DLCEYKEKVD I
Download this sequence
in fasta format
Download all sequences for 4.2.99.18
in fasta format
in csv (Excel, OpenOffice) format
Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
30136
Asahara H.,Wistort P.M.,Bank J.F.,Bakerian R.H.,Cunningham R.P.
Purification and characterization of Escherichia coli endonuclease III from the cloned nth gene.
Biochemistry
28
4444-4449
1989
30137
Aiba H.,Baba T.,Fujita K.,Hayashi K.,Inada T.,Isono K.,Itoh T.,Kasai H.,Kashimoto K.,Kimura S.,Kitakawa M.,Kitagawa M.,Makino K.,Miki T.,Mizobuchi K.,Mori H.,Mori T.,Motomura K.,Nakade S.,Nakamura Y.,Nashimoto H.,Nishio Y.,Oshima T.,Saito N.,Sampei G.,Seki Y.,Sivasundaram S.,Tagami H.,Takeda J.,Takemoto K.,Takeuchi Y.,Wada C.,Yamamoto Y.,Horiuchi T.
A 570-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 28.0-40.1 min region on the linkage map.
DNA Res.
3
363-377
1996
30138
Blattner F.R.,Plunkett G. III,Bloch C.A.,Perna N.T.,Burland V.,Riley M.,Collado-Vides J.,Glasner J.D.,Rode C.K.,Mayhew G.F.,Gregor J.,Davis N.W.,Kirkpatrick H.A.,Goeden M.A.,Rose D.J.,Mau B.,Shao Y.
The complete genome sequence of Escherichia coli K-12.
Science
277
1453-1462
1997
30139
Hayashi K.,Morooka N.,Yamamoto Y.,Fujita K.,Isono K.,Choi S.,Ohtsubo E.,Baba T.,Wanner B.L.,Mori H.,Horiuchi T.
Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.
Mol. Syst. Biol.
2
0-0
2006
30140
Breimer L.H.,Lindahl T.
DNA glycosylase activities for thymine residues damaged by ring saturation, fragmentation, or ring contraction are functions of endonuclease III in Escherichia coli.
J. Biol. Chem.
259
5543-5548
1984
30141
Kim J.,Linn S.
The mechanisms of action of E. coli endonuclease III and T4 UV endonuclease (endonuclease V) at AP sites.
Nucleic Acids Res.
16
1135-1141
1988
30142
Cunningham R.P.,Ahern H.,Xing D.,Thayer M.M.,Tainer J.A.
Structure and function of Escherichia coli endonuclease III.
Ann. N. Y. Acad. Sci.
726
215-222
1994
30143
Kuo C.-F.,McRee D.,Fisher C.L.,O'Handley S.F.,Cunningham R.P.,Tainer J.A.
Atomic structure of the DNA repair [4Fe-4S] enzyme endonuclease III.
Science
258
434-440
1992
30144
Thayer M.M.,Ahern H.,Xing D.,Cunningham R.P.,Tainer J.A.
Novel DNA binding motifs in the DNA repair enzyme endonuclease III crystal structure.
EMBO J.
14
4108-4120
1995