Sequence of FAXD_TROCA
EC Number:3.4.21.6
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
selective cleavage of Arg-/-Thr and then Arg-/-Ile bonds in prothrombin to form thrombin
Other sequences found for EC No. 3.4.21.6
General information:
Sequence
0 MAPQLLLCLI LTFLWSLPEA ESNVFLKSKV ANRFLQRTKR SNSLFEEIRP GNIERECIEE
60 KCSKEEAREV FEDNEKTETF WNVYVDGDQC SSNPCHYRGT CKDGIGSYTC TCLPNYEGKN
120 CEKVLYQSCR VDNGNCWHFC KRVQSETQCS CAESYRLGVD GHSCVAEGDF SCGRNIKARN
180 KREASLPDFV QSQKATLLKK SDNPSPDIRI VNGMDCKLGE CPWQAVLINE KGEVFCGGTI
240 LSPIHVLTAA HCINQTKSVS VIVGEIDISR KETRRLLSVD KIYVHTKFVP PNYYYVHQNF
300 DRVAYDYDIA IIRMKTPIQF SENVVPACLP TADFANEVLM KQDSGIVSGF GRIQFKQPTS
360 NTLKVITVPY VDRHTCMLSS DFRITQNMFC AGYDTLPQDA CQGDSGGPHI TAYRDTHFIT
420 GIISWGEGCA RKGKYGVYTK VSKFIPWIKK IMSLK
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
291411
St Pierre L.,Masci P.P.,Filippovich I.,Sorokina N.,Marsh N.,Miller D.J.,Lavin M.F.
Comparative analysis of prothrombin activators from the venom of Australian elapids.
Mol. Biol. Evol.
22
1853-1864
2005
291412
Reza M.A.,Swarup S.,Kini R.M.
Structure of two genes encoding parallel prothrombin activators in Tropidechis carinatus snake: gene duplication and recruitment of factor X gene to the venom gland.
J. Thromb. Haemost.
5
117-126
2007
291413
Joseph J.S.,Chung M.C.M.,Jeyaseelan K.,Kini R.M.
Amino acid sequence of trocarin, a prothrombin activator from Tropidechis carinatus venom: its structural similarity to coagulation factor Xa.
Blood
94
621-631
1999
291414
Manjunatha Kini R.,Morita T.,Rosing J.
Classification and nomenclature of prothrombin activators isolated from snake venoms.
Thromb. Haemost.
86
710-711
2001
291415
Joseph J.S.,Valiyaveettil M.,Gowda D.C.,Kini R.M.
Occurrence of O-linked Xyl-GlcNAc and Xyl-Glc disaccharides in trocarin, a factor Xa homolog from snake venom.
J. Thromb. Haemost.
1
545-550
2003
