Sequence of CP8B1_MOUSE
EC Number:1.14.14.139
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
5beta-cholestane-3alpha,7alpha-diol + [reduced NADPH-hemoprotein reductase] + O2 = 5beta-cholestane-3alpha,7alpha,12alpha-triol + [oxidized NADPH-hemoprotein reductase] + H2O
Other sequences found for EC No. 1.14.14.139
General information:
Sequence
0 MTLWCTVLGA LLTVVGCLCL SLLLRHRRPW EPPLDKGFVP WLGHSMAFRK NMFEFLKGMR
60 AKHGDVFTVQ LGGQYFTFVM DPLSFGPIIK NTEKALDFQS YAKELVLKVF GYQSVDGDHR
120 MIHLASTKHL MGQGLEELNQ AMLDSLSLVM LGPKGSSLGA SSWCEDGLFH FCYRILFKAG
180 FLSLFGYTKD KQQDLDEADE LFRKFRRFDF LFPRFVYSLL GPREWVEVSQ LQRLFHQRLS
240 VEQNLEKDGI SCWLGYMLQF LREQGIASSM QDKFNFMMLW ASQGNTGPTC FWVLLFLLKH
300 QDAMKAVREE ATRVMGKARL EAKKSFTFTP SALKHTPVLD SVMEESLRLC ATPTLLRVVQ
360 EDYVLKMASG QEYQIRRGDK VALFPYLSVH MDPDIHPEPT AFKYDRFLNP DGTRKVDFYK
420 SGKKIHHYSM PWGSGVSKCP GRFFALSEMK TFVLLMIMYF DFKLVDPDIP VPPIDPRRWG
480 FGTSQPSHEV RFLYRLKPVQ
Download this sequence
in fasta formatDownload all sequences for 1.14.14.139
in fasta format
in csv (Excel, OpenOffice) formatSequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
279448
Gaafvels M.,Olin M.,Chowdhary B.P.,Raudsepp T.,Andersson U.,Persson B.,Jansson M.,Bjoerkhem I.,Eggertsen G.
Structure and chromosomal assignment of the sterol 12alpha-hydroxylase gene (CYP8B1) in human and mouse: eukaryotic cytochrome P-450 gene devoid of introns.
Genomics
56
184-196
1999
279449
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
279450
Li-Hawkins J.,Gaafvels M.,Olin M.,Lund E.G.,Andersson U.,Schuster G.,Bjoerkhem I.,Russell D.W.,Eggertsen G.
Cholic acid mediates negative feedback regulation of bile acid synthesis in mice.
J. Clin. Invest.
110
1191-1200
2002
279451
Huttlin E.L.,Jedrychowski M.P.,Elias J.E.,Goswami T.,Rad R.,Beausoleil S.A.,Villen J.,Haas W.,Sowa M.E.,Gygi S.P.
A tissue-specific atlas of mouse protein phosphorylation and expression.
Cell
143
1174-1189
2010
279452
Bertaggia E.,Jensen K.K.,Castro-Perez J.,Xu Y.,Di Paolo G.,Chan R.B.,Wang L.,Haeusler R.A.
Cyp8b1 ablation prevents Western diet-induced weight gain and hepatic steatosis because of impaired fat absorption.
Am. J. Physiol.
313
0-0
2017
