Sequence of AURKA_HUMAN
EC Number:2.7.11.1
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
ATP + a [protein]-(L-serine/L-threonine) = ADP + a [protein]-(L-serine/L-threonine) phosphate
Other sequences found for EC No. 2.7.11.1
General information:
Sequence
0 MDRSKENCIS GPVKATAPVG GPKRVLVTQQ FPCQNPLPVN SGQAQRVLCP SNSSQRIPLQ
60 AQKLVSSHKP VQNQKQKQLQ ATSVPHPVSR PLNNTQKSKQ PLPSAPENNP EEELASKQKN
120 EESKKRQWAL EDFEIGRPLG KGKFGNVYLA REKQSKFILA LKVLFKAQLE KAGVEHQLRR
180 EVEIQSHLRH PNILRLYGYF HDATRVYLIL EYAPLGTVYR ELQKLSKFDE QRTATYITEL
240 ANALSYCHSK RVIHRDIKPE NLLLGSAGEL KIADFGWSVH APSSRRTTLC GTLDYLPPEM
300 IEGRMHDEKV DLWSLGVLCY EFLVGKPPFE ANTYQETYKR ISRVEFTFPD FVTEGARDLI
360 SRLLKHNPSQ RPMLREVLEH PWITANSSKP SNCQNKESAS KQS
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
268832
Kimura M.,Kotani S.,Hattori T.,Sumi N.,Yoshioka T.,Todokoro K.,Okano Y.
Cell cycle-dependent expression and spindle pole localization of a novel human protein kinase, Aik, related to Aurora of Drosophila and yeast Ipl1.
J. Biol. Chem.
272
13766-13771
1997
268833
Shindo M.,Nakano H.,Kuroyanagi H.,Shirasawa T.,Mihara M.,Gilbert D.J.,Jenkins N.A.,Copeland N.G.,Yagita H.,Okumura K.
cDNA cloning, expression, subcellular localization, and chromosomal assignment of mammalian aurora homologues, aurora-related kinase (ARK) 1 and 2.
Biochem. Biophys. Res. Commun.
244
285-292
1998
268834
Zhou H.,Kuang J.,Zhong L.,Kuo W.-L.,Gray J.W.,Sahin A.,Brinkley B.R.,Sen S.
Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation.
Nat. Genet.
20
189-193
1998
268836
Deloukas P.,Matthews L.H.,Ashurst J.L.,Burton J.,Gilbert J.G.R.,Jones M.,Stavrides G.,Almeida J.P.,Babbage A.K.,Bagguley C.L.,Bailey J.,Barlow K.F.,Bates K.N.,Beard L.M.,Beare D.M.,Beasley O.P.,Bird C.P.,Blakey S.E.,Bridgeman A.M.,Brown A.J.,Buck D.,Burrill W.D.,Butler A.P.,Carder C.,Carter N.P.,Chapman J.C.,Clamp M.,Clark G.,Clark L.N.,Clark S.Y.,Clee C.M.,Clegg S.,Cobley V.E.,Collier R.E.,Connor R.E.,Corby N.R.,Coulson A.,Coville G.J.,Deadman R.,Dhami P.D.,Dunn M.,Ellington A.G.,Frankland J.A.,Fraser A.,French L.,Garner P.,Grafham D.V.,Griffiths C.,Griffiths M.N.D.,Gwilliam R.,Hall R.E.,Hammond S.,Harley J.L.,Heath P.D.,Ho S.,Holden J.L.,Howden P.J.,Huckle E.,Hunt A.R.,Hunt S.E.,Jekosch K.,Johnson C.M.,Johnson D.,Kay M.P.,Kimberley A.M.,King A.,Knights A.,Laird G.K.,Lawlor S.,Lehvaeslaiho M.H.,Leversha M.A.,Lloyd C.,Lloyd D.M.,Lovell J.D.,Marsh V.L.,Martin S.L.,McConnachie L.J.,McLay K.,McMurray A.A.,Milne S.A.,Mistry D.,Moore M.J.F.,Mullikin J.C.,Nickerson T.,Oliver K.,Parker A.,Patel R.,Pearce T.A.V.,Peck A.I.,Phillimore B.J.C.T.,Prathalingam S.R.,Plumb R.W.,Ramsay H.,Rice C.M.,Ross M.T.,Scott C.E.,Sehra H.K.,Shownkeen R.,Sims S.,Skuce C.D.,Smith M.L.,Soderlund C.,Steward C.A.,Sulston J.E.,Swann R.M.,Sycamore N.,Taylor R.,Tee L.,Thomas D.W.,Thorpe A.,Tracey A.,Tromans A.C.,Vaudin M.,Wall M.,Wallis J.M.,Whitehead S.L.,Whittaker P.,Willey D.L.,Williams L.,Williams S.A.,Wilming L.,Wray P.W.,Hubbard T.,Durbin R.M.,Bentley D.R.,Beck S.,Rogers J.
The DNA sequence and comparative analysis of human chromosome 20.
Nature
414
865-871
2001
268838
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
268839
Bischoff J.R.,Anderson L.,Zhu Y.,Mossie K.,Ng L.,Souza B.,Schryver B.,Flanagan P.,Clairvoyant F.,Ginther C.,Chan C.S.,Novotny M.,Slamon D.J.,Plowman G.D.
A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers.
EMBO J.
17
3052-3065
1998
268840
Honda K.,Mihara H.,Kato Y.,Yamaguchi A.,Tanaka H.,Yasuda H.,Furukawa K.,Urano T.
Degradation of human Aurora2 protein kinase by the anaphase-promoting complex-ubiquitin-proteasome pathway.
Oncogene
19
2812-2819
2000
268841
Walter A.O.,Seghezzi W.,Korver W.,Sheung J.,Lees E.
The mitotic serine/threonine kinase Aurora2/AIK is regulated by phosphorylation and degradation.
Oncogene
19
4906-4916
2000
268842
Katayama H.,Zhou H.,Li Q.,Tatsuka M.,Sen S.
Interaction and feedback regulation between STK15/BTAK/Aurora-A kinase and protein phosphatase 1 through mitotic cell division cycle.
J. Biol. Chem.
276
46219-46224
2001
268843
Sugimoto K.,Urano T.,Zushi H.,Inoue K.,Tasaka H.,Tachibana M.,Dotsu M.
Molecular dynamics of Aurora-A kinase in living mitotic cells simultaneously visualized with histone H3 and nuclear membrane protein importinalpha.
Cell Struct. Funct.
27
457-467
2002
268844
Marumoto T.,Hirota T.,Morisaki T.,Kunitoku N.,Zhang D.,Ichikawa Y.,Sasayama T.,Kuninaka S.,Mimori T.,Tamaki N.,Kimura M.,Okano Y.,Saya H.
Roles of aurora-A kinase in mitotic entry and G2 checkpoint in mammalian cells.
Genes Cells
7
1173-1182
2002
268845
Tanaka M.,Ueda A.,Kanamori H.,Ideguchi H.,Yang J.,Kitajima S.,Ishigatsubo Y.
Cell-cycle-dependent regulation of human aurora A transcription is mediated by periodic repression of E4TF1.
J. Biol. Chem.
277
10719-10726
2002
268846
Hirota T.,Kunitoku N.,Sasayama T.,Marumoto T.,Zhang D.,Nitta M.,Hatakeyama K.,Saya H.
Aurora-A and an interacting activator, the LIM protein Ajuba, are required for mitotic commitment in human cells.
Cell
114
585-598
2003
268847
Marumoto T.,Honda S.,Hara T.,Nitta M.,Hirota T.,Kohmura E.,Saya H.
Aurora-A kinase maintains the fidelity of early and late mitotic events in HeLa cells.
J. Biol. Chem.
278
51786-51795
2003
268848
Conte N.,Delaval B.,Ginestier C.,Ferrand A.,Isnardon D.,Larroque C.,Prigent C.,Seraphin B.,Jacquemier J.,Birnbaum D.
TACC1-chTOG-Aurora A protein complex in breast cancer.
Oncogene
22
8102-8116
2003
268849
Toji S.,Yabuta N.,Hosomi T.,Nishihara S.,Kobayashi T.,Suzuki S.,Tamai K.,Nojima H.
The centrosomal protein Lats2 is a phosphorylation target of Aurora-A kinase.
Genes Cells
9
383-397
2004
268850
Ouchi M.,Fujiuchi N.,Sasai K.,Katayama H.,Minamishima Y.A.,Ongusaha P.P.,Deng C.,Sen S.,Lee S.W.,Ouchi T.
BRCA1 phosphorylation by Aurora-A in the regulation of G2 to M transition.
J. Biol. Chem.
279
19643-19648
2004
268851
Ouchi M.,Fujiuchi N.,Sasai K.,Katayama H.,Minamishima Y.A.,Ongusaha P.P.,Deng C.,Sen S.,Lee S.W.,Ouchi T.
J. Biol. Chem.
290
22311-22311
2015
268852
Dutertre S.,Cazales M.,Quaranta M.,Froment C.,Trabut V.,Dozier C.,Mirey G.,Bouche J.P.,Theis-Febvre N.,Schmitt E.,Monsarrat B.,Prigent C.,Ducommun B.
Phosphorylation of CDC25B by Aurora-A at the centrosome contributes to the G2-M transition.
J. Cell Sci.
117
2523-2531
2004
268853
Katayama H.,Sasai K.,Kawai H.,Yuan Z.M.,Bondaruk J.,Suzuki F.,Fujii S.,Arlinghaus R.B.,Czerniak B.A.,Sen S.
Phosphorylation by aurora kinase A induces Mdm2-mediated destabilization and inhibition of p53.
Nat. Genet.
36
55-62
2004
268854
Sasayama T.,Marumoto T.,Kunitoku N.,Zhang D.,Tamaki N.,Kohmura E.,Saya H.,Hirota T.
Over-expression of Aurora-A targets cytoplasmic polyadenylation element binding protein and promotes mRNA polyadenylation of Cdk1 and cyclin B1.
Genes Cells
10
627-638
2005
268855
Zhao Z.S.,Lim J.P.,Ng Y.W.,Lim L.,Manser E.
The GIT-associated kinase PAK targets to the centrosome and regulates Aurora-A.
Mol. Cell
20
237-249
2005
268856
Yu C.T.,Hsu J.M.,Lee Y.C.,Tsou A.P.,Chou C.K.,Huang C.Y.
Phosphorylation and stabilization of HURP by Aurora-A: implication of HURP as a transforming target of Aurora-A.
Mol. Cell. Biol.
25
5789-5800
2005
268857
Hutterer A.,Berdnik D.,Wirtz-Peitz F.,Zigman M.,Schleiffer A.,Knoblich J.A.
Mitotic activation of the kinase Aurora-A requires its binding partner Bora.
Dev. Cell
11
147-157
2006
268858
Sankaran S.,Crone D.E.,Palazzo R.E.,Parvin J.D.
Aurora-A kinase regulates breast cancer associated gene 1 inhibition of centrosome-dependent microtubule nucleation.
Cancer Res.
67
11186-11194
2007
268859
Pugacheva E.N.,Jablonski S.A.,Hartman T.R.,Henske E.P.,Golemis E.A.
HEF1-dependent Aurora A activation induces disassembly of the primary cilium.
Cell
129
1351-1363
2007
268860
Birkenfeld J.,Nalbant P.,Bohl B.P.,Pertz O.,Hahn K.M.,Bokoch G.M.
GEF-H1 modulates localized RhoA activation during cytokinesis under the control of mitotic kinases.
Dev. Cell
12
699-712
2007
268861
Horn V.,Thelu J.,Garcia A.,Albiges-Rizo C.,Block M.R.,Viallet J.
Functional interaction of Aurora-A and PP2A during mitosis.
Mol. Biol. Cell
18
1233-1241
2007
268862
North B.J.,Verdin E.
Interphase nucleo-cytoplasmic shuttling and localization of SIRT2 during mitosis.
PLoS ONE
2
0-0
2007
268863
Manfredi M.G.,Ecsedy J.A.,Meetze K.A.,Balani S.K.,Burenkova O.,Chen W.,Galvin K.M.,Hoar K.M.,Huck J.J.,LeRoy P.J.,Ray E.T.,Sells T.B.,Stringer B.,Stroud S.G.,Vos T.J.,Weatherhead G.S.,Wysong D.R.,Zhang M.,Bolen J.B.,Claiborne C.F.
Antitumor activity of MLN8054, an orally active small-molecule inhibitor of Aurora A kinase.
Proc. Natl. Acad. Sci. U.S.A.
104
4106-4111
2007
268864
Daub H.,Olsen J.V.,Bairlein M.,Gnad F.,Oppermann F.S.,Korner R.,Greff Z.,Keri G.,Stemmann O.,Mann M.
Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
Mol. Cell
31
438-448
2008
268865
Macurek L.,Lindqvist A.,Lim D.,Lampson M.A.,Klompmaker R.,Freire R.,Clouin C.,Taylor S.S.,Yaffe M.B.,Medema R.H.
Polo-like kinase-1 is activated by aurora A to promote checkpoint recovery.
Nature
455
119-123
2008
268866
Khazaei M.R.,Puschel A.W.
Phosphorylation of the par polarity complex protein Par3 at serine 962 is mediated by aurora A and regulates its function in neuronal polarity.
J. Biol. Chem.
284
33571-33579
2009
268867
Jang C.Y.,Coppinger J.A.,Seki A.,Yates J.R. III,Fang G.
Plk1 and Aurora A regulate the depolymerase activity and the cellular localization of Kif2a.
J. Cell Sci.
122
1334-1341
2009
268868
Mori D.,Yamada M.,Mimori-Kiyosue Y.,Shirai Y.,Suzuki A.,Ohno S.,Saya H.,Wynshaw-Boris A.,Hirotsune S.
An essential role of the aPKC-Aurora A-NDEL1 pathway in neurite elongation by modulation of microtubule dynamics.
Nat. Cell Biol.
11
1057-1068
2009
268869
Fu J.,Bian M.,Liu J.,Jiang Q.,Zhang C.
A single amino acid change converts Aurora-A into Aurora-B-like kinase in terms of partner specificity and cellular function.
Proc. Natl. Acad. Sci. U.S.A.
106
6939-6944
2009
268870
Kinzel D.,Boldt K.,Davis E.E.,Burtscher I.,Trumbach D.,Diplas B.,Attie-Bitach T.,Wurst W.,Katsanis N.,Ueffing M.,Lickert H.
Pitchfork regulates primary cilia disassembly and left-right asymmetry.
Dev. Cell
19
66-77
2010
268871
Lieu A.S.,Cheng T.S.,Chou C.H.,Wu C.H.,Hsu C.Y.,Huang C.Y.,Chang L.K.,Loh J.K.,Chang C.S.,Hsu C.M.,Howng S.L.,Hong Y.R.
Functional characterization of AIBp, a novel Aurora-A binding protein in centrosome structure and spindle formation.
Int. J. Oncol.
37
429-436
2010
268872
Sanchez R.,Pantoja-Uceda D.,Prieto J.,Diercks T.,Marcaida M.J.,Montoya G.,Campos-Olivas R.,Blanco F.J.
Solution structure of human growth arrest and DNA damage 45alpha (Gadd45alpha) and its interactions with proliferating cell nuclear antigen (PCNA) and Aurora A kinase.
J. Biol. Chem.
285
22196-22201
2010
268873
Burkard T.R.,Planyavsky M.,Kaupe I.,Breitwieser F.P.,Buerckstuemmer T.,Bennett K.L.,Superti-Furga G.,Colinge J.
Initial characterization of the human central proteome.
BMC Syst. Biol.
5
17-17
2011
268874
Platica M.,Ionescu A.,Ivan E.,Holland J.F.,Mandeli J.,Platica O.
PAR, a protein involved in the cell cycle, is functionally related to chromosomal passenger proteins.
Int. J. Oncol.
38
777-785
2011
268875
Carmena M.,Earnshaw W.C.
The cellular geography of aurora kinases.
Nat. Rev. Mol. Cell Biol.
4
842-854
2003
268876
Lukasiewicz K.B.,Lingle W.L.
Aurora A, centrosome structure, and the centrosome cycle.
Environ. Mol. Mutagen.
50
602-619
2009
268877
Kim H.S.,Vassilopoulos A.,Wang R.H.,Lahusen T.,Xiao Z.,Xu X.,Li C.,Veenstra T.D.,Li B.,Yu H.,Ji J.,Wang X.W.,Park S.H.,Cha Y.I.,Gius D.,Deng C.X.
SIRT2 maintains genome integrity and suppresses tumorigenesis through regulating APC/C activity.
Cancer Cell
20
487-499
2011
268878
Ma N.,Matsunaga S.,Morimoto A.,Sakashita G.,Urano T.,Uchiyama S.,Fukui K.
The nuclear scaffold protein SAF-A is required for kinetochore-microtubule attachment and contributes to the targeting of Aurora-A to mitotic spindles.
J. Cell Sci.
124
394-404
2011
268879
Moghe S.,Jiang F.,Miura Y.,Cerny R.L.,Tsai M.Y.,Furukawa M.
The CUL3-KLHL18 ligase regulates mitotic entry and ubiquitylates Aurora-A.
Biol. Open
1
82-91
2012
268880
Ikeda M.,Chiba S.,Ohashi K.,Mizuno K.
Furry protein promotes Aurora A-mediated polo-like kinase 1 activation.
J. Biol. Chem.
287
27670-27681
2012
268881
Ohta S.,Wood L.,Toramoto I.,Yagyu K.,Fukagawa T.,Earnshaw W.C.
CENP-32 is required to maintain centrosomal dominance in bipolar spindle assembly.
Mol. Biol. Cell
26
1225-1237
2015
268882
Douglas P.,Ye R.,Morrice N.,Britton S.,Trinkle-Mulcahy L.,Lees-Miller S.P.
Phosphorylation of SAF-A/hnRNP-U serine 59 by polo-like kinase 1 is required for mitosis.
Mol. Cell. Biol.
35
2699-2713
2015
268883
Kotak S.,Afshar K.,Busso C.,Goenczy P.
Aurora A kinase regulates proper spindle positioning in C. elegans and in human cells.
J. Cell Sci.
129
3015-3025
2016
268884
Hendriks I.A.,Lyon D.,Young C.,Jensen L.J.,Vertegaal A.C.,Nielsen M.L.
Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.
Nat. Struct. Mol. Biol.
24
325-336
2017
268885
Kamran M.,Long Z.J.,Xu D.,Lv S.S.,Liu B.,Wang C.L.,Xu J.,Lam E.W.,Liu Q.
Aurora kinase A regulates Survivin stability through targeting FBXL7 in gastric cancer drug resistance and prognosis.
Oncogenesis
6
0-0
2017
268886
Jiao A.L.,Perales R.,Umbreit N.T.,Haswell J.R.,Piper M.E.,Adams B.D.,Pellman D.,Kennedy S.,Slack F.J.
Human nuclear RNAi-defective 2 (NRDE2) is an essential RNA splicing factor.
RNA
25
352-363
2019
268887
Cheetham G.M.,Knegtel R.M.,Coll J.T.,Renwick S.B.,Swenson L.,Weber P.,Lippke J.A.,Austen D.A.
Crystal structure of aurora-2, an oncogenic serine/threonine kinase.
J. Biol. Chem.
277
42419-42422
2002
268888
Nowakowski J.,Cronin C.N.,McRee D.E.,Knuth M.W.,Nelson C.G.,Pavletich N.P.,Rogers J.,Sang B.C.,Scheibe D.N.,Swanson R.V.,Thompson D.A.
Structures of the cancer-related Aurora-A, FAK, and EphA2 protein kinases from nanovolume crystallography.
Structure
10
1659-1667
2002
268889
Bayliss R.,Sardon T.,Vernos I.,Conti E.
Structural basis of Aurora-A activation by TPX2 at the mitotic spindle.
Mol. Cell
12
851-862
2003
268890
Heron N.M.,Anderson M.,Blowers D.P.,Breed J.,Eden J.M.,Green S.,Hill G.B.,Johnson T.,Jung F.H.,McMiken H.H.,Mortlock A.A.,Pannifer A.D.,Pauptit R.A.,Pink J.,Roberts N.J.,Rowsell S.
SAR and inhibitor complex structure determination of a novel class of potent and specific Aurora kinase inhibitors.
Bioorg. Med. Chem. Lett.
16
1320-1323
2006
268891
Fancelli D.,Moll J.,Varasi M.,Bravo R.,Artico R.,Berta D.,Bindi S.,Cameron A.,Candiani I.,Cappella P.,Carpinelli P.,Croci W.,Forte B.,Giorgini M.L.,Klapwijk J.,Marsiglio A.,Pesenti E.,Rocchetti M.,Roletto F.,Severino D.,Soncini C.,Storici P.,Tonani R.,Zugnoni P.,Vianello P.
1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazoles: identification of a potent aurora kinase inhibitor with a favorable antitumor kinase inhibition profile.
J. Med. Chem.
49
7247-7251
2006
268892
Zhao B.,Smallwood A.,Yang J.,Koretke K.,Nurse K.,Calamari A.,Kirkpatrick R.B.,Lai Z.
Modulation of kinase-inhibitor interactions by auxiliary protein binding: crystallography studies on Aurora A interactions with VX-680 and with TPX2.
Protein Sci.
17
1791-1797
2008
268893
Bibby R.A.,Tang C.,Faisal A.,Drosopoulos K.,Lubbe S.,Houlston R.,Bayliss R.,Linardopoulos S.
A cancer-associated aurora A mutant is mislocalized and misregulated due to loss of interaction with TPX2.
J. Biol. Chem.
284
33177-33184
2009
268894
Coumar M.S.,Leou J.S.,Shukla P.,Wu J.S.,Dixit A.K.,Lin W.H.,Chang C.Y.,Lien T.W.,Tan U.K.,Chen C.H.,Hsu J.T.,Chao Y.S.,Wu S.Y.,Hsieh H.P.
Structure-based drug design of novel Aurora kinase A inhibitors: structural basis for potency and specificity.
J. Med. Chem.
52
1050-1062
2009
268895
Aliagas-Martin I.,Burdick D.,Corson L.,Dotson J.,Drummond J.,Fields C.,Huang O.W.,Hunsaker T.,Kleinheinz T.,Krueger E.,Liang J.,Moffat J.,Phillips G.,Pulk R.,Rawson T.E.,Ultsch M.,Walker L.,Wiesmann C.,Zhang B.,Zhu B.Y.,Cochran A.G.
A class of 2,4-bisanilinopyrimidine Aurora A inhibitors with unusually high selectivity against Aurora B.
J. Med. Chem.
52
3300-3307
2009
268896
Richards M.W.,Burgess S.G.,Poon E.,Carstensen A.,Eilers M.,Chesler L.,Bayliss R.
Structural basis of N-Myc binding by Aurora-A and its destabilization by kinase inhibitors.
Proc. Natl. Acad. Sci. U.S.A.
113
13726-13731
2016
268897
Kimura M.T.,Mori T.,Conroy J.,Nowak N.J.,Satomi S.,Tamai K.,Nagase H.
Two functional coding single nucleotide polymorphisms in STK15 (Aurora-A) coordinately increase esophageal cancer risk.
Cancer Res.
65
3548-3554
2005
268898
Chen L.,Ao X.,Ren Q.,Wang Z.N.,Lu C.,Xu Y.,Jiang L.,Luo Y.,Xu H.M.,Zhang X.
Linkage disequilibrium and haplotype analysis of two single nucleotide polymorphisms in STK15 in Chinese.
Yi Chuan Xue Bao
32
331-336
2005
268899
Tchatchou S.,Wirtenberger M.,Hemminki K.,Sutter C.,Meindl A.,Wappenschmidt B.,Kiechle M.,Bugert P.,Schmutzler R.K.,Bartram C.R.,Burwinkel B.
Aurora kinases A and B and familial breast cancer risk.
Cancer Lett.
247
266-272
2007
268900
Greenman C.,Stephens P.,Smith R.,Dalgliesh G.L.,Hunter C.,Bignell G.,Davies H.,Teague J.,Butler A.,Stevens C.,Edkins S.,O'Meara S.,Vastrik I.,Schmidt E.E.,Avis T.,Barthorpe S.,Bhamra G.,Buck G.,Choudhury B.,Clements J.,Cole J.,Dicks E.,Forbes S.,Gray K.,Halliday K.,Harrison R.,Hills K.,Hinton J.,Jenkinson A.,Jones D.,Menzies A.,Mironenko T.,Perry J.,Raine K.,Richardson D.,Shepherd R.,Small A.,Tofts C.,Varian J.,Webb T.,West S.,Widaa S.,Yates A.,Cahill D.P.,Louis D.N.,Goldstraw P.,Nicholson A.G.,Brasseur F.,Looijenga L.,Weber B.L.,Chiew Y.-E.,DeFazio A.,Greaves M.F.,Green A.R.,Campbell P.,Birney E.,Easton D.F.,Chenevix-Trench G.,Tan M.-H.,Khoo S.K.,Teh B.T.,Yuen S.T.,Leung S.Y.,Wooster R.,Futreal P.A.,Stratton M.R.
Patterns of somatic mutation in human cancer genomes.
Nature
446
153-158
2007
268901
Carvalhal S.,Ribeiro S.A.,Arocena M.,Kasciukovic T.,Temme A.,Koehler K.,Huebner A.,Griffis E.R.
The nucleoporin ALADIN regulates Aurora A localization to ensure robust mitotic spindle formation.
Mol. Biol. Cell
26
3424-3438
2015
