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Sequence of TYRO_MOUSE

EC Number:1.14.18.1

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
tyrosinase
P11344
Mus musculus
533
60606
Reaction
2 L-dopa + O2 = 2 dopaquinone + 2 H2O
Other sequences found for EC No. 1.14.18.1

General information:

Sequence
show sequence in fasta format
  0 MFLAVLYCLL WSFQISDGHF PRACASSKNL LAKECCPPWM GDGSPCGQLS GRGSCQDILL
 60 SSAPSGPQFP FKGVDDRESW PSVFYNRTCQ CSGNFMGFNC GNCKFGFGGP NCTEKRVLIR
120 RNIFDLSVSE KNKFFSYLTL AKHTISSVYV IPTGTYGQMN NGSTPMFNDI NIYDLFVWMH
180 YYVSRDTLLG GSEIWRDIDF AHEAPGFLPW HRLFLLLWEQ EIRELTGDEN FTVPYWDWRD
240 AENCDICTDE YLGGRHPENP NLLSPASFFS SWQIICSRSE EYNSHQVLCD GTPEGPLLRN
300 PGNHDKAKTP RLPSSADVEF CLSLTQYESG SMDRTANFSF RNTLEGFASP LTGIADPSQS
360 SMHNALHIFM NGTMSQVQGS ANDPIFLLHH AFVDSIFEQW LRRHRPLLEV YPEANAPIGH
420 NRDSYMVPFI PLYRNGDFFI TSKDLGYDYS YLQESDPGFY RNYIEPYLEQ ASRIWPWLLG
480 AALVGAVIAA ALSGLSSRLC LQKKKKKKQP QEERQPLLMD KDDYHSLLYQ SHL
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
245982
Kwon B.S.,Wakulchik M.,Haq A.K.,Halaban R.,Kestler D.
Sequence analysis of mouse tyrosinase cDNA and the effect of melanotropin on its gene expression.
Biochem. Biophys. Res. Commun.
153
1301-1309
1988
245983
Mueller G.,Ruppert S.,Schmid E.,Schuetz G.
Functional analysis of alternatively spliced tyrosinase gene transcripts.
EMBO J.
7
2723-2730
1988
245984
Kwon B.S.,Halaban R.,Chintamaneni C.
Molecular basis of mouse Himalayan mutation.
Biochem. Biophys. Res. Commun.
161
252-260
1989
245985
Terao M.,Tabe L.,Garattini E.,Sartori D.,Studer M.,Mintz B.
Isolation and characterization of variant cDNAs encoding mouse tyrosinase.
Biochem. Biophys. Res. Commun.
159
848-853
1989
245986
Yamamoto H.,Takeuchi S.,Kudo T.,Sato C.,Takeuchi T.
Melanin production in cultured albino melanocytes transfected with mouse tyrosinase cDNA.
Jpn. J. Genet.
64
121-135
1989
245987
Kwon B.S.,Haq A.K.,Wakulchik M.,Kestler D.,Barton D.E.,Francke U.,Lamoreux M.L.,Whitney J.B. III,Halaban R.
Isolation, chromosomal mapping, and expression of the mouse tyrosinase gene.
J. Invest. Dermatol.
93
589-594
1989
245988
Shibahara S.,Okinaga S.,Tomita Y.,Takeda A.,Yamamoto H.,Sato M.,Takeuchi T.
A point mutation in the tyrosinase gene of BALB/c albino mouse causing the cysteine-->serine substitution at position 85.
Eur. J. Biochem.
189
455-461
1990
245989
Tsukamoto K.,Jackson I.J.,Urabe K.,Montague P.M.,Hearing V.J.
A second tyrosinase-related protein, TRP-2, is a melanogenic enzyme termed DOPAchrome tautomerase.
EMBO J.
11
519-526
1992
245990
Marubashi S.,Shimada H.,Fukuda M.,Ohbayashi N.
RUTBC1 functions as a GTPase-activating protein for Rab32/38 and regulates melanogenic enzyme trafficking in melanocytes.
J. Biol. Chem.
291
1427-1440
2016
245991
Beermann F.,Ruppert S.,Hummler E.,Bosch F.X.,Mueller G.,Ruether U.,Schuetz G.
Rescue of the albino phenotype by introduction of a functional tyrosinase gene into mice.
EMBO J.
9
2819-2826
1990