Sequence of CP4A2_RAT
EC Number:1.14.14.80
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
a long-chain fatty acid + [reduced NADPH-hemoprotein reductase] + O2 = an omega-hydroxy-long-chain fatty acid + [oxidized NADPH-hemoprotein reductase] + H2O
Other sequences found for EC No. 1.14.14.80
General information:
Sequence
0 MGFSVFSPTR SLDGVSGFFQ GAFLLSLFLV LFKAVQFYLR RQWLLKALEK FPSTPSHWLW
60 GHNLKDREFQ QVLTWVEKFP GACLQWLSGS TARVLLYDPD YVKVVLGRSD PKPYQSLAPW
120 IGYGLLLLNG KKWFQHRRML TPAFHYDILK PYVKIMADSV SIMLDKWEKL DDQDHPLEIF
180 HYVSLMTLDT VMKCAFSHQG SVQLDVNSRS YTKAVEDLNN LIFFRVRSAF YGNSIIYNMS
240 SDGRLSRRAC QIAHEHTDGV IKTRKAQLQN EEELQKARKK RHLDFLDILL FAKMEDGKSL
300 SDEDLRAEVD TFMFEGHDTT ASGISWVFYA LATHPEHQER CREEVQSILG DGTSVTWDHL
360 DQMPYTTMCI KEALRLYSPV PSVSRELSSP VTFPDGRSIP KGIRVTILIY GLHHNPSYWP
420 NPKVFDPSRF SPDSPRHSHA YLPFSGGARN CIGKQFAMNE LKVAVALTLL RFELLPDPTR
480 IPVPMPRLVL KSKNGIHLRL KKLR
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
20380
Kimura S.,Hanioka N.,Matsunaga E.,Gonzalez F.J.
The rat clofibrate-inducible CYP4A gene subfamily. I. Complete intron and exon sequence of the CYP4A1 and CYP4A2 genes, unique exon organization, and identification of a conserved 19-bp upstream element.
DNA
8
503-516
1989
20381
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
20382
Kawashima H.,Kusunose E.,Kubota I.,Maekawa M.,Kusunose M.
Purification and NH2-terminal amino acid sequences of human and rat kidney fatty acid omega-hydroxylases.
Biochim. Biophys. Acta
1123
156-162
1992
20383
Imaoka S.,Nagashima K.,Funae Y.
Characterization of three cytochrome P450s purified from renal microsomes of untreated male rats and comparison with human renal cytochrome P450.
Arch. Biochem. Biophys.
276
473-480
1990
20384
Hoch U.,Zhang Z.,Kroetz D.L.,Ortiz de Montellano P.R.
Structural determination of the substrate specificities and regioselectivities of the rat and human fatty acid omega-hydroxylases.
Arch. Biochem. Biophys.
373
63-71
2000
20385
Hoch U.,Falck J.R.,de Montellano P.R.
Molecular basis for the omega-regiospecificity of the CYP4A2 and CYP4A3 fatty acid hydroxylases.
J. Biol. Chem.
275
26952-26958
2000
20386
Hoch U.,Ortiz de Montellano P.R.
Covalently linked heme in cytochrome P4504A fatty acid hydroxylases.
J. Biol. Chem.
276
11339-11346
2001
20387
Lundby A.,Secher A.,Lage K.,Nordsborg N.B.,Dmytriyev A.,Lundby C.,Olsen J.V.
Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.
Nat. Commun.
3
876-876
2012
