Sequence of MMP14_HUMAN

membrane-type matrix metalloproteinase-1

P50281

582

65894

189131

Sato H.,Takino T.,Okada Y.,Cao J.,Shinagawa A.,Yamamoto E.,Seiki M.

A matrix metalloproteinase expressed on the surface of invasive tumour cells.

Nature

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189132

Takino T.,Sato H.,Yamamoto E.,Seiki M.

Cloning of a human gene potentially encoding a novel matrix metalloproteinase having a C-terminal transmembrane domain.

Gene

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189133

Okada A.,Bellocq J.-P.,Rouyer N.,Chenard M.P.,Rio M.C.,Chambon P.,Basset P.

Membrane-type matrix metalloproteinase (MT-MMP) gene is expressed in stromal cells of human colon, breast, and head and neck carcinomas.

Proc. Natl. Acad. Sci. U.S.A.

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189134

Will H.,Hinzmann B.

cDNA sequence and mRNA tissue distribution of a novel human matrix metalloproteinase with a potential transmembrane segment.

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189136

Lohi J.L.,Westermarck J.,Kaehaeri V.M.,Keski-Oja J.

Regulation of membrane-type matrix metalloproteinase-1 expression by growth factors and phorbol 12-myristate 13-acetate.

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189137

Ota T.,Suzuki Y.,Nishikawa T.,Otsuki T.,Sugiyama T.,Irie R.,Wakamatsu A.,Hayashi K.,Sato H.,Nagai K.,Kimura K.,Makita H.,Sekine M.,Obayashi M.,Nishi T.,Shibahara T.,Tanaka T.,Ishii S.,Yamamoto J.,Saito K.,Kawai Y.,Isono Y.,Nakamura Y.,Nagahari K.,Murakami K.,Yasuda T.,Iwayanagi T.,Wagatsuma M.,Shiratori A.,Sudo H.,Hosoiri T.,Kaku Y.,Kodaira H.,Kondo H.,Sugawara M.,Takahashi M.,Kanda K.,Yokoi T.,Furuya T.,Kikkawa E.,Omura Y.,Abe K.,Kamihara K.,Katsuta N.,Sato K.,Tanikawa M.,Yamazaki M.,Ninomiya K.,Ishibashi T.,Yamashita H.,Murakawa K.,Fujimori K.,Tanai H.,Kimata M.,Watanabe M.,Hiraoka S.,Chiba Y.,Ishida S.,Ono Y.,Takiguchi S.,Watanabe S.,Yosida M.,Hotuta T.,Kusano J.,Kanehori K.,Takahashi-Fujii A.,Hara H.,Tanase T.-O.,Nomura Y.,Togiya S.,Komai F.,Hara R.,Takeuchi K.,Arita M.,Imose N.,Musashino K.,Yuuki H.,Oshima A.,Sasaki N.,Aotsuka S.,Yoshikawa Y.,Matsunawa H.,Ichihara T.,Shiohata N.,Sano S.,Moriya S.,Momiyama H.,Satoh N.,Takami S.,Terashima Y.,Suzuki O.,Nakagawa S.,Senoh A.,Mizoguchi H.,Goto Y.,Shimizu F.,Wakebe H.,Hishigaki H.,Watanabe T.,Sugiyama A.,Takemoto M.,Kawakami B.,Yamazaki M.,Watanabe K.,Kumagai A.,Itakura S.,Fukuzumi Y.,Fujimori Y.,Komiyama M.,Tashiro H.,Tanigami A.,Fujiwara T.,Ono T.,Yamada K.,Fujii Y.,Ozaki K.,Hirao M.,Ohmori Y.,Kawabata A.,Hikiji T.,Kobatake N.,Inagaki H.,Ikema Y.,Okamoto S.,Okitani R.,Kawakami T.,Noguchi S.,Itoh T.,Shigeta K.,Senba T.,Matsumura K.,Nakajima Y.,Mizuno T.,Morinaga M.,Sasaki M.,Togashi T.,Oyama M.,Hata H.,Watanabe M.,Komatsu T.,Mizushima-Sugano J.,Satoh T.,Shirai Y.,Takahashi Y.,Nakagawa K.,Okumura K.,Nagase T.,Nomura N.,Kikuchi H.,Masuho Y.,Yamashita R.,Nakai K.,Yada T.,Nakamura Y.,Ohara O.,Isogai T.,Sugano S.

Complete sequencing and characterization of 21,243 full-length human cDNAs.

Nat. Genet.

36

40-45

2004

189139

Heilig R.,Eckenberg R.,Petit J.-L.,Fonknechten N.,Da Silva C.,Cattolico L.,Levy M.,Barbe V.,De Berardinis V.,Ureta-Vidal A.,Pelletier E.,Vico V.,Anthouard V.,Rowen L.,Madan A.,Qin S.,Sun H.,Du H.,Pepin K.,Artiguenave F.,Robert C.,Cruaud C.,Bruels T.,Jaillon O.,Friedlander L.,Samson G.,Brottier P.,Cure S.,Segurens B.,Aniere F.,Samain S.,Crespeau H.,Abbasi N.,Aiach N.,Boscus D.,Dickhoff R.,Dors M.,Dubois I.,Friedman C.,Gouyvenoux M.,James R.,Madan A.,Mairey-Estrada B.,Mangenot S.,Martins N.,Menard M.,Oztas S.,Ratcliffe A.,Shaffer T.,Trask B.,Vacherie B.,Bellemere C.,Belser C.,Besnard-Gonnet M.,Bartol-Mavel D.,Boutard M.,Briez-Silla S.,Combette S.,Dufosse-Laurent V.,Ferron C.,Lechaplais C.,Louesse C.,Muselet D.,Magdelenat G.,Pateau E.,Petit E.,Sirvain-Trukniewicz P.,Trybou A.,Vega-Czarny N.,Bataille E.,Bluet E.,Bordelais I.,Dubois M.,Dumont C.,Guerin T.,Haffray S.,Hammadi R.,Muanga J.,Pellouin V.,Robert D.,Wunderle E.,Gauguet G.,Roy A.,Sainte-Marthe L.,Verdier J.,Verdier-Discala C.,Hillier L.W.,Fulton L.,McPherson J.,Matsuda F.,Wilson R.,Scarpelli C.,Gyapay G.,Wincker P.,Saurin W.,Quetier F.,Waterston R.,Hood L.,Weissenbach J.

The DNA sequence and analysis of human chromosome 14.

Nature

421

601-607

2003

189140

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

Genome Res.

14

2121-2127

2004

189141

Sato H.,Kinoshita T.,Takino T.,Nakayama K.,Seiki M.

Activation of a recombinant membrane type 1-matrix metalloproteinase (MT1-MMP) by furin and its interaction with tissue inhibitor of metalloproteinases (TIMP)-2.

FEBS Lett.

393

101-104

1996

189142

Noda K.,Ishida S.,Inoue M.,Obata K.,Oguchi Y.,Okada Y.,Ikeda E.

Production and activation of matrix metalloproteinase-2 in proliferative diabetic retinopathy.

Invest. Ophthalmol. Vis. Sci.

44

2163-2170

2003

189143

Chi A.,Valencia J.C.,Hu Z.-Z.,Watabe H.,Yamaguchi H.,Mangini N.J.,Huang H.,Canfield V.A.,Cheng K.C.,Yang F.,Abe R.,Yamagishi S.,Shabanowitz J.,Hearing V.J.,Wu C.,Appella E.,Hunt D.F.

Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes.

J. Proteome Res.

5

3135-3144

2006

189144

Bonnomet A.,Polette M.,Strumane K.,Gilles C.,Dalstein V.,Kileztky C.,Berx G.,van Roy F.,Birembaut P.,Nawrocki-Raby B.

The E-cadherin-repressed hNanos1 gene induces tumor cell invasion by upregulating MT1-MMP expression.

Oncogene

27

3692-3699

2008

189145

Golubkov V.S.,Chekanov A.V.,Cieplak P.,Aleshin A.E.,Chernov A.V.,Zhu W.,Radichev I.A.,Zhang D.,Dong P.D.,Strongin A.Y.

The Wnt/planar cell polarity protein-tyrosine kinase-7 (PTK7) is a highly efficient proteolytic target of membrane type-1 matrix metalloproteinase: implications in cancer and embryogenesis.

J. Biol. Chem.

285

35740-35749

2010

189146

Jin G.,Zhang F.,Chan K.M.,Xavier Wong H.L.,Liu B.,Cheah K.S.,Liu X.,Mauch C.,Liu D.,Zhou Z.

MT1-MMP cleaves Dll1 to negatively regulate Notch signalling to maintain normal B-cell development.

EMBO J.

30

2281-2293

2011

189147

Gu G.,Zhao D.,Yin Z.,Liu P.

BST-2 binding with cellular MT1-MMP blocks cell growth and migration via decreasing MMP2 activity.

J. Cell. Biochem.

113

1013-1021

2012

189148

Cork S.M.,Kaur B.,Devi N.S.,Cooper L.,Saltz J.H.,Sandberg E.M.,Kaluz S.,Van Meir E.G.

A proprotein convertase/MMP-14 proteolytic cascade releases a novel 40 kDa vasculostatin from tumor suppressor BAI1.

Oncogene

31

5144-5152

2012

189149

Bordoli M.R.,Yum J.,Breitkopf S.B.,Thon J.N.,Italiano J.E. Jr.,Xiao J.,Worby C.,Wong S.K.,Lin G.,Edenius M.,Keller T.L.,Asara J.M.,Dixon J.E.,Yeo C.Y.,Whitman M.

A secreted tyrosine kinase acts in the extracellular environment.

Cell

158

1033-1044

2014

189150

Fernandez-Catalan C.,Bode W.,Huber R.,Turk D.,Calvete J.J.,Lichte A.,Tschesche H.,Maskos K.

Crystal structure of the complex formed by the membrane type 1-matrix metalloproteinase with the tissue inhibitor of metalloproteinases-2, the soluble progelatinase A receptor.

EMBO J.

17

5238-5248

1998

189151

Evans B.R.,Mosig R.A.,Lobl M.,Martignetti C.R.,Camacho C.,Grum-Tokars V.,Glucksman M.J.,Martignetti J.A.

Mutation of membrane type-1 metalloproteinase, MT1-MMP, causes the multicentric osteolysis and arthritis disease Winchester syndrome.

Am. J. Hum. Genet.

91

572-576

2012