Sequence of LOX5_RAT
EC Number:1.13.11.34
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
(6E,8Z,11Z,14Z)-(5S)-5-hydroperoxyicosa-6,8,11,14-tetraenoate = leukotriene A4 + H2O
Other sequences found for EC No. 1.13.11.34
General information:
Sequence
0 MPSYTVTVAT GSQWFAGTDD YIYLSLIGSA GCSEKHLLDK AFYNDFERGG RDSYDVTVDE
60 ELGEIYLVKI EKRKYRLHDD WYLKYITLKT PHDYIEFPCY RWITGEGEIV LRDGCAKLAR
120 DDQIHILKQH RRKELETRQK QYRWMEWNPG FPLSIDAKCH KDLPRDIQFD SEKGVDFVLN
180 YSKAMENLFI NRFMHMFQSS WHDFADFEKI FVKISNTISE RVKNHWQEDL MFGYQFLNGC
240 NPVLIKRCTE LPKKLPVTTE MVECSLERQL SLEQEVQEGN IFIVDYELLD GIDANKTDPC
300 THQFLAAPIC LLYKNLANKI VPIAIQLNQT PGEKNPIFLP TDSKYDWLLA KIWVRSSDFH
360 IHQTITHLLR THLVSEVFGI AMYRQLPAVH PLFKLLVAHV RFTIAINTKA REQLNCEYGL
420 FDKANATGGG GHVQMVQRAV QDLTYSSLCF PEAIKARGMD NTEDIPYYFY RDDGLLVWEA
480 IQSFTTEVVS IYYEDDQVVE EDQELQDFVK DVYVYGMRGR KASGFPKSIK SREKLSEYLT
540 VVIFTASAQH AAVNFGQYDW CSWIPNAPPT MRAPPPTAKG VVTIEQIVDT LPDRGRSCWH
600 LGAVWALSQF QENELFLGMY PEEHFIEKPV KEAMIRFRKN LEAIVSVIAE RNKNKKLPYY
660 YLSPDRIPNS VAI
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
183799
Balcarek J.M.,Theisen T.W.,Cook M.N.,Varrichio A.,Hwang S.-M.,Strohsacker M.W.,Crooke S.T.
Isolation and characterization of a cDNA clone encoding rat 5-lipoxygenase.
J. Biol. Chem.
263
13937-13941
1988
183800
Minor W.,Steczko J.,Bolin J.T.,Otwinowski Z.,Axelrod B.
Crystallographic determination of the active site iron and its ligands in soybean lipoxygenase L-1.
Biochemistry
32
6320-6323
1993
