Sequence of LARA_LACPL
EC Number:5.1.2.1
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
lactate racemase
F9USS9
Lactiplantibacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1)
424
46239
Reaction
(S)-Lactate = (R)-lactate
Other sequences found for EC No. 5.1.2.1
General information:
Sequence
0 MVAIDLPYDK RTITAQIDDE NYAGKLVSQA ATYHNKLSEQ ETVEKSLDNP IGSDKLEELA
60 RGKHNIVIIS SDHTRPVPSH IITPILLRRL RSVAPDARIR ILVATGFHRP STHEELVNKY
120 GEDIVNNEEI VMHVSTDDSS MVKIGQLPSG GDCIINKVAA EADLLISEGF IESHFFAGFS
180 GGRKSVLPGI ASYKTIMANH SGEFINSPKA RTGNLMHNSI HKDMVYAART AKLAFIINVV
240 LDEDKKIIGS FAGDMEAAHK VGCDFVKELS SVPAIDCDIA ISTNGGYPLD QNIYQAVKGM
300 TAAEATNKEG GTIIMVAGAR DGHGGEGFYH NLADVDDPKE FLDQAINTPR LKTIPDQWTA
360 QIFARILVHH HVIFVSDLVD PDLITNMHME LAKTLDEAME KAYAREGQAA KVTVIPDGLG
420 VIVK
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
181665
Kleerebezem M.,Boekhorst J.,van Kranenburg R.,Molenaar D.,Kuipers O.P.,Leer R.,Tarchini R.,Peters S.A.,Sandbrink H.M.,Fiers M.W.E.J.,Stiekema W.,Klein Lankhorst R.M.,Bron P.A.,Hoffer S.M.,Nierop Groot M.N.,Kerkhoven R.,De Vries M.,Ursing B.,De Vos W.M.,Siezen R.J.
Complete genome sequence of Lactobacillus plantarum WCFS1.
Proc. Natl. Acad. Sci. U.S.A.
100
1990-1995
2003
181666
Siezen R.J.,Francke C.,Renckens B.,Boekhorst J.,Wels M.,Kleerebezem M.,van Hijum S.A.
Complete resequencing and reannotation of the Lactobacillus plantarum WCFS1 genome.
J. Bacteriol.
194
195-196
2012
181667
Goffin P.,Deghorain M.,Mainardi J.L.,Tytgat I.,Champomier-Verges M.C.,Kleerebezem M.,Hols P.
Lactate racemization as a rescue pathway for supplying D-lactate to the cell wall biosynthesis machinery in Lactobacillus plantarum.
J. Bacteriol.
187
6750-6761
2005
181668
Desguin B.,Goffin P.,Viaene E.,Kleerebezem M.,Martin-Diaconescu V.,Maroney M.J.,Declercq J.P.,Soumillion P.,Hols P.
Lactate racemase is a nickel-dependent enzyme activated by a widespread maturation system.
Nat. Commun.
5
3615-3615
2014
181669
Desguin B.,Goffin P.,Bakouche N.,Diman A.,Viaene E.,Dandoy D.,Fontaine L.,Hallet B.,Hols P.
Enantioselective regulation of lactate racemization by LarR in Lactobacillus plantarum.
J. Bacteriol.
197
219-230
2015
181670
Desguin B.,Soumillion P.,Hols P.,Hausinger R.P.
Nickel-pincer cofactor biosynthesis involves LarB-catalyzed pyridinium carboxylation and LarE-dependent sacrificial sulfur insertion.
Proc. Natl. Acad. Sci. U.S.A.
113
5598-5603
2016
181671
Desguin B.,Zhang T.,Soumillion P.,Hols P.,Hu J.,Hausinger R.P.
METALLOPROTEINS. A tethered niacin-derived pincer complex with a nickel-carbon bond in lactate racemase.
Science
349
66-69
2015
