Sequence of FAXC_PSETE
EC Number:3.4.21.6
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
selective cleavage of Arg-/-Thr and then Arg-/-Ile bonds in prothrombin to form thrombin
Other sequences found for EC No. 3.4.21.6
General information:
Sequence
0 MAPQLLLCLI LTFLWSLPEA ESNVFLKSKV ANRFLQRTKR ANSLVEEFKS GNIERECIEE
60 RCSKEEAREV FEDDEKTETF WNVYVDGDQC SSNPCHYRGI CKDGIGSYTC TCLSGYEGKN
120 CERVLYKSCR VDNGNCWHFC KSVQNDIQCS CAEGYLLGED GHSCVAGGNF SCGRNIKTRN
180 KREASLPDFV QSHNATLLKK SDNPSPDIRI VNGMDCKLGE CPWQAALVDD KKGVFCGGTI
240 LSPIYVLTAA HCINETETIS VVVGEIDRSR AETGPLLSVD KVYVHKKFVP PKKSQEFYEK
300 FDLVSYDYDI AIIQMKTPIQ FSENVVPACL PTADFANQVL MKQDFGIVSG FGGIFERGPN
360 SKTLKVLKVP YVDRHTCMLS SNFPITPTMF CAGYDTLPQD ACQGDSGGPH ITAYRDTHFI
420 TGIVSWGEGC ARKGRYGIYT KLSKFIPWIK RIMRQKLPST ESSTGRL
Download this sequence
in fasta formatDownload all sequences for 3.4.21.6
in fasta format
in csv (Excel, OpenOffice) formatSequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
160772
Rao V.S.,Swarup S.,Kini R.M.
The catalytic subunit of pseutarin C, a group C prothrombin activator from the venom of Pseudonaja textilis, is structurally similar to mammalian blood coagulation factor Xa.
Thromb. Haemost.
92
509-521
2004
160773
Filippovich I.,Sorokina N.,St Pierre L.,Flight S.,de Jersey J.,Perry N.,Masci P.P.,Lavin M.F.
Cloning and functional expression of venom prothrombin activator protease from Pseudonaja textilis with whole blood procoagulant activity.
Br. J. Haematol.
131
237-246
2005
160774
Reza M.A.,Swarup S.,Kini R.M.
Structure of two genes encoding parallel prothrombin activators in Tropidechis carinatus snake: gene duplication and recruitment of factor X gene to the venom gland.
J. Thromb. Haemost.
5
117-126
2007
160775
Rao V.S.,Kini R.M.
Pseutarin C, a prothrombin activator from Pseudonaja textilis venom: its structural and functional similarity to mammalian coagulation factor Xa-Va complex.
Thromb. Haemost.
88
611-619
2002
160776
Masci P.P.,Whitaker A.N.,de Jersey J.
Purification and characterization of a prothrombin activator from the venom of the Australian brown snake, Pseudonaja textilis textilis.
Biochem. Int.
17
825-835
1988
160777
Manjunatha Kini R.,Morita T.,Rosing J.
Classification and nomenclature of prothrombin activators isolated from snake venoms.
Thromb. Haemost.
86
710-711
2001
160778
Earl S.T.,Masci P.P.,de Jersey J.,Lavin M.F.,Dixon J.
Drug development from Australian elapid snake venoms and the Venomics pipeline of candidates for haemostasis: Textilinin-1 (Q8008), Haempatch (Q8009) and CoVase (V0801).
Toxicon
59
456-463
2012
160779
Lechtenberg B.C.,Murray-Rust T.A.,Johnson D.J.,Adams T.E.,Krishnaswamy S.,Camire R.M.,Huntington J.A.
Crystal structure of the prothrombinase complex from the venom of Pseudonaja textilis.
Blood
122
2777-2783
2013
