Sequence of FA10_HUMAN

coagulation factor Xa

P00742

488

54732

160091

Messier T.L.,Pittman D.D.,Long G.L.,Kaufman R.J.,Church W.R.

Cloning and expression in COS-1 cells of a full-length cDNA encoding human coagulation factor X.

Gene

99

291-294

1991

160092

Leytus S.P.,Foster D.C.,Kurachi K.,Davie E.W.

Gene for human factor X: a blood coagulation factor whose gene organization is essentially identical with that of factor IX and protein C.

Biochemistry

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5098-5102

1986

160094

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

Genome Res.

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2121-2127

2004

160095

Fung M.R.,Hay C.W.,McGillivray R.T.A.

Characterization of an almost full-length cDNA coding for human blood coagulation factor X.

Proc. Natl. Acad. Sci. U.S.A.

82

3591-3595

1985

160096

Kaul R.K.,Hildebrand B.,Roberts S.,Jagadeeswaran P.

Isolation and characterization of human blood-coagulation factor X cDNA.

Gene

41

311-314

1986

160097

McMullen B.A.,Fujikawa K.,Kisiel W.,Sasagawa T.,Howald W.N.,Kwa E.Y.,Weinstein B.

Complete amino acid sequence of the light chain of human blood coagulation factor X: evidence for identification of residue 63 as beta-hydroxyaspartic acid.

Biochemistry

22

2875-2884

1983

160098

Leytus S.P.,Chung D.W.,Kisiel W.,Kurachi K.,Davie E.W.

Characterization of a cDNA coding for human factor X.

Proc. Natl. Acad. Sci. U.S.A.

81

3699-3702

1984

160099

Inoue K.,Morita T.

Identification of O-linked oligosaccharide chains in the activation peptides of blood coagulation factor X. The role of the carbohydrate moieties in the activation of factor X.

Eur. J. Biochem.

218

153-163

1993

160100

Jagadeeswaran P.,Reddy S.V.,Rao K.J.,Hamsabhushanam K.,Lyman G.

Cloning and characterization of the 5' end (exon 1) of the gene encoding human factor X.

Gene

84

517-519

1989

160101

Suzuki K.,Nishioka J.,Kusumoto H.,Hashimoto S.

Mechanism of inhibition of activated protein C by protein C inhibitor.

J. Biochem.

95

187-195

1984

160102

Plescia J.,Altieri D.C.

Activation of Mac-1 (CD11b/CD18)-bound factor X by released cathepsin G defines an alternative pathway of leucocyte initiation of coagulation.

Biochem. J.

319

873-879

1996

160103

Huang X.,Dementiev A.,Olson S.T.,Gettins P.G.

Basis for the specificity and activation of the serpin protein Z-dependent proteinase inhibitor (ZPI) as an inhibitor of membrane-associated factor Xa.

J. Biol. Chem.

285

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2010

160104

Halim A.,Nilsson J.,Ruetschi U.,Hesse C.,Larson G.

Human urinary glycoproteomics; attachment site specific analysis of N- and O-linked glycosylations by CID and ECD.

Mol. Cell. Proteomics

11

1-17

2012

160105

Padmanabhan K.,Padmanabhan K.P.,Tulinsky A.,Park C.H.,Bode W.,Huber R.,Blankenship D.T.,Cardin A.D.,Kisiel W.

Structure of human des(1-45) factor Xa at 2.2-A resolution.

J. Mol. Biol.

232

947-966

1993

160106

Kamata K.,Kawamoto H.,Honma T.,Iwama T.,Kim S.H.

Structural basis for chemical inhibition of human blood coagulation factor Xa.

Proc. Natl. Acad. Sci. U.S.A.

95

6630-6635

1998

160107

Kochanny M.J.,Adler M.,Ewing J.,Griedel B.D.,Ho E.,Karanjawala R.,Lee W.,Lentz D.,Liang A.M.,Morrissey M.M.,Phillips G.B.,Post J.,Sacchi K.L.,Sakata S.T.,Subramanyam B.,Vergona R.,Walters J.,White K.A.,Whitlow M.,Ye B.,Zhao Z.,Shaw K.J.

Substituted thiophene-anthranilamides as potent inhibitors of human factor Xa.

Bioorg. Med. Chem.

15

2127-2146

2007

160108

Reddy S.V.,Zhou Z.Q.,Rao K.J.,Scott J.P.,Watzke H.,High K.A.,Jagadeeswaran P.

Molecular characterization of human factor XSan Antonio.

Blood

74

1486-1490

1989

160109

Watzke H.H.,Lechner K.,Roberts H.R.,Reddy S.V.,Welsch D.J.,Friedman P.,Mahr G.,Jagadeeswaran P.,Monroe D.M.,High K.A.

Molecular defect (Gla+14TO: hereditary factor X deficiency (factor X 'Vorarlberg').

J. Biol. Chem.

265

11982-11989

1990

160110

James H.L.,Girolami A.,Fair D.S.

Molecular defect in coagulation factor XFriuli results from a substitution of serine for proline at position 343.

Blood

77

317-323

1991

160111

Marchetti G.,Castaman G.,Pinotti M.,Lunghi B.,Di Iasio M.G.,Ruggieri M.,Rodeghiero F.,Bernardi F.

Molecular bases of CRM+ factor X deficiency: a frequent mutation (Ser334Pro) in the catalytic domain and a substitution (Glu102Lys) in the second EGF-like domain.

Br. J. Haematol.

90

910-915

1995

160112

Bezeaud A.,Miyata T.,Helley D.,Zeng Y.Z.,Kato H.,Aillaud M.F.,Juhan-Vague I.,Guillin M.C.

Functional consequences of the Ser334-->Pro mutation in a human factor X variant (factor XMarseille).

Eur. J. Biochem.

234

140-147

1995

160113

Kim D.J.,Thompson A.R.,James H.L.

Factor XKetchikan: a variant molecule in which Gly replaces a Gla residue at position 14 in the light chain.

Hum. Genet.

95

212-214

1995

160114

Messier T.L.,Wong C.Y.,Bovill E.G.,Long G.L.,Church W.R.

Factor X Stockton: a mild bleeding diathesis associated with an active site mutation in factor X.

Blood Coagul. Fibrinolysis

7

5-14

1996

160115

Rudolph A.E.,Mullane M.P.,Porche-Sorbet R.,Tsuda S.,Miletich J.P.

Factor XSt. Louis II. Identification of a glycine substitution at residue 7 and characterization of the recombinant protein.

J. Biol. Chem.

271

28601-28606

1996

160116

Zama T.,Murata M.,Watanabe R.,Yokoyama K.,Moriki T.,Ambo H.,Murakami H.,Kikuchi M.,Ikeda Y.

A family with hereditary factor X deficiency with a point mutation Gla32 to Gln in the Gla domain (factor X Tokyo).

Br. J. Haematol.

106

809-811

1999

160117

Cargill M.,Altshuler D.,Ireland J.,Sklar P.,Ardlie K.,Patil N.,Shaw N.,Lane C.R.,Lim E.P.,Kalyanaraman N.,Nemesh J.,Ziaugra L.,Friedland L.,Rolfe A.,Warrington J.,Lipshutz R.,Daley G.Q.,Lander E.S.

Characterization of single-nucleotide polymorphisms in coding regions of human genes.

Nat. Genet.

22

231-238

1999

160119

Millar D.S.,Elliston L.,Deex P.,Krawczak M.,Wacey A.I.,Reynaud J.,Nieuwenhuis H.K.,Bolton-Maggs P.,Mannucci P.M.,Reverter J.C.,Cachia P.,Pasi K.J.,Layton D.M.,Cooper D.N.

Molecular analysis of the genotype-phenotype relationship in factor X deficiency.

Hum. Genet.

106

249-257

2000

160120

Forberg E.,Huhmann I.,Jimenez-Boj E.,Watzke H.H.

The impact of Glu102Lys on the factor X function in a patient with a doubly homozygous factor X deficiency (Gla14Lys and Glu102Lys).

Thromb. Haemost.

83

234-238

2000

160121

Simioni P.,Vianello F.,Kalafatis M.,Barzon L.,Ladogana S.,Paolucci P.,Carotenuto M.,Dal Bello F.,Palu G.,Girolami A.

A dysfunctional factor X (factor X San Giovanni Rotondo) present at homozygous and double heterozygous level: identification of a novel microdeletion (delC556) and missense mutation (Lys(408)-->Asn) in the factor X gene. A study of an Italian family.

Thromb. Res.

101

219-230

2001

160122

Vianello F.,Lombardi A.M.,Boldrin C.,Luni S.,Girolami A.

A new factor X defect (factor X Padua 3): a compound heterozygous between true deficiency (Gly(380)-->Arg) and an abnormality (Ser(334)-->Pro).

Thromb. Res.

104

257-264

2001

160123

Vianello F.,Lombardi A.M.,Bello F.D.,Palu G.,Zanon E.,Girolami A.

A novel type I factor X variant (factor X Cys350Phe) due to loss of a disulfide bond in the catalytic domain.

Blood Coagul. Fibrinolysis

14

401-405

2003

160124

Pinotti M.,Camire R.M.,Baroni M.,Rajab A.,Marchetti G.,Bernardi F.

Impaired prothrombinase activity of factor X Gly381Asp results in severe familial CRM+ FX deficiency.

Thromb. Haemost.

89

243-248

2003

160125

Pinotti M.,Monti M.,Baroni M.,Marchetti G.,Bernardi F.

Molecular characterization of factor X deficiency associated with borderline plasma factor X level.

Haematologica

89

501-502

2004

160126

Isshiki I.,Favier R.,Moriki T.,Uchida T.,Ishihara H.,Van Dreden P.,Murata M.,Ikeda Y.

Genetic analysis of hereditary factor X deficiency in a French patient of Sri Lankan ancestry: in vitro expression study identified Gly366Ser substitution as the molecular basis of the dysfunctional factor X.

Blood Coagul. Fibrinolysis

16

9-16

2005

160127

Al-Hilali A.,Wulff K.,Abdel-Razeq H.,Saud K.A.,Al-Gaili F.,Herrmann F.H.

Analysis of the novel factor X gene mutation Glu51Lys in two families with factor X-Riyadh anomaly.

Thromb. Haemost.

97

542-545

2007

160128

Chafa O.,Tagzirt M.,Tapon-Bretaudiere J.,Reghis A.,Fischer A.M.,LeBonniec B.F.

Characterization of a homozygous Gly11Val mutation in the Gla domain of coagulation factor X.

Thromb. Res.

124

144-148

2009

160129

Abdel-Azeim S.,Oliva R.,Chermak E.,De Cristofaro R.,Cavallo L.

Molecular dynamics characterization of five pathogenic Factor X mutants associated with decreased catalytic activity.

Biochemistry

53

6992-7001

2014

160130

Epcacan S.,Menegatti M.,Akbayram S.,Cairo A.,Peyvandi F.,Oner A.F.

Frequency of the p.Gly262Asp mutation in congenital Factor X deficiency.

Eur. J. Clin. Invest.

45

1087-1091

2015