Sequence of CYPH1_SALMI
EC Number:1.14.14.175
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
abieta-8,11,13-triene + [reduced NADPH-hemoprotein reductase] + O2 = ferruginol + [oxidized NADPH-hemoprotein reductase] + H2O
Other sequences found for EC No. 1.14.14.175
General information:
Sequence
0 MDSFPLLAAL FFIAATITFL SFRRRRNLPP GPFPYPIVGN MLQLGANPHQ VFAKLSKRYG
60 PLMSIHLGSL YTVIVSSPEM AKEILHRHGQ VFSGRTIAQA VHACDHDKIS MGFLPVASEW
120 RDMRKICKEQ MFSNQSMEAS QGLRRQKLQQ LLDHVQKCSD SGRAVDIREA AFITTLNLMS
180 ATLFSSQATE FDSKATMEFK EIIEGVATIV GVPNFADYFP ILRPFDPQGV KRRADVFFGK
240 LLAKIEGYLN ERLESKRANP NAPKKDDFLE IVVDIIQANE FKLKTHHFTH LMLDLFVGGS
300 DTNTTSIEWA MSELVMNPDK MARLKAELKS VAGDEKIVDE SAMPKLPYLQ AVIKEVMRIH
360 PPGPLLLPRK AESDQEVNGY LIPKGTQILI NAYAIGRDPS IWTDPETFDP ERFLDNKIDF
420 KGQDYELLPF GSGRRVCPGM PLATRILHMA TATLVHNFDW KLEDDSTAAA DHAGELFGVA
480 VRRAVPLRII PIVKS
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
150379
Guo J.,Zhou Y.J.,Hillwig M.L.,Shen Y.,Yang L.,Wang Y.,Zhang X.,Liu W.,Peters R.J.,Chen X.,Zhao Z.K.,Huang L.
CYP76AH1 catalyzes turnover of miltiradiene in tanshinones biosynthesis and enables heterologous production of ferruginol in yeasts.
Proc. Natl. Acad. Sci. U.S.A.
110
12108-12113
2013
150380
Zi J.,Peters R.J.
Characterization of CYP76AH4 clarifies phenolic diterpenoid biosynthesis in the Lamiaceae.
Org. Biomol. Chem.
11
7650-7652
2013
150381
Scheler U.,Brandt W.,Porzel A.,Rothe K.,Manzano D.,Bozic D.,Papaefthimiou D.,Balcke G.U.,Henning A.,Lohse S.,Marillonnet S.,Kanellis A.K.,Ferrer A.,Tissier A.
Elucidation of the biosynthesis of carnosic acid and its reconstitution in yeast.
Nat. Commun.
7
12942-12942
2016
150382
Gu M.,Wang M.,Guo J.,Shi C.,Deng J.,Huang L.,Huang L.,Chang Z.
Crystal structure of CYP76AH1 in 4-PI-bound state from Salvia miltiorrhiza.
Biochem. Biophys. Res. Commun.
511
813-819
2019
